Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL245004 | 1.00 | LMNA (0.54) | LMNAMAPTMAPK1ALDH1A1TSHR | |
| SCHEMBL245323 | 1.00 | LMNA (0.54) | LMNAMAPTMAPK1ALDH1A1TSHR | |
| SCHEMBL4975150 | 0.94 | LMNA (0.43) | LMNAMAPTMAPK1ALDH1A1TSHR | |
| SCHEMBL4980922 | 0.92 | LMNA (0.41) | LMNAMAPTMAPK1ALDH1A1TSHR | |
| SCHEMBL244516 | 0.92 | PRKCA (0.50) | LMNAPRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL27466370 | 0.87 | TSHR (0.37) | LMNAMAPTMAPK1ALDH1A1TSHR | |
| SCHEMBL4975784 | 0.86 | TSHR (0.41) | LMNAALDH1A1TSHR | |
| SCHEMBL11743243 | 0.83 | LMNA (0.59) | LMNAMAPTMAPK1ALDH1A1TSHR | |
| SCHEMBL242459 | 0.81 | ALDH1A1 (0.52) | LMNAMAPTALDH1A1TSHRKDM4E | |
| SCHEMBL27481368 | 0.80 | TSHR (0.37) | LMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9221738-B2 | Method and system for purifying monomers | EVONIK RÖHM GMBH (DE) | 2015-12-29 | — | — | US | disclosed |
| US-20120000764-A1 | METHOD AND SYSTEM FOR PURIFYING MONOMERS | EVONIK DEGUSSA GMBH (DE) | 2012-01-05 | — | — | US | disclosed |