Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4975150 | 0.98 | LMNA (0.43) | LMNATSHRALDH1A1MAPTMAPK1 | |
| SCHEMBL27466370 | 0.94 | TSHR (0.37) | LMNATSHRALDH1A1MAPTMAPK1 | |
| SCHEMBL4975784 | 0.93 | TSHR (0.41) | LMNATSHRALDH1A1 | |
| SCHEMBL245323 | 0.92 | LMNA (0.54) | LMNATSHRALDH1A1MAPTMAPK1 | |
| SCHEMBL245029 | 0.92 | LMNA (0.54) | LMNATSHRALDH1A1MAPTMAPK1 | |
| SCHEMBL245004 | 0.92 | LMNA (0.54) | LMNATSHRALDH1A1MAPTMAPK1 | |
| SCHEMBL27481368 | 0.87 | TSHR (0.37) | LMNATSHRALDH1A1 | |
| SCHEMBL244516 | 0.85 | PRKCA (0.50) | LMNAPRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL649529 | 0.85 | TSHR (0.45) | TSHRALDH1A1 | |
| SCHEMBL242459 | 0.82 | ALDH1A1 (0.52) | LMNATSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015272-A1 | Polyurethane Foam | FRITZ NAUER AG (CH) | 2008-01-17 | — | — | US | disclosed |
| US-7132459-B1 | Moulded bodies made from a polyurethane material, production and use thereof | FRITZ NAUER AG (CH) | 2006-11-07 | — | — | US | disclosed |