SCHEMBL49759

SCHEMBL49759

CC[CH]Nc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
NPSR1 Q6W5P4 2/20 0.42
IDO1 P14902 1/20 0.42
TSHR P16473 1/20 0.42
NPC1 O15118 1/20 0.41
NFKB1 P19838 1/20 0.41
RAB9A P51151 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
KDM4E B2RXH2 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP2C19 P33261 1/20 0.40
GAA P10253 2/20 0.39
MAPT P10636 2/20 0.39
KMT2A Q03164 1/20 0.39
ALOX5 P09917 1/20 0.39
HSD17B10 Q99714 2/20 0.39
TAS2R38 P59533 1/20 0.39
NAPRT Q6XQN6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6244975 0.81 ALDH1A1 (0.44) ALDH1A1NPSR1TSHRKDM4ECYP1A2
SCHEMBL3929076 0.78 SOAT2 (0.41) ALDH1A1NPSR1TSHRKDM4ECYP1A2
SCHEMBL23128456 0.76 KDM4E (0.46) ALDH1A1NPSR1IDO1TSHRNPC1
SCHEMBL6542992 0.76 KDM4E (0.46) ALDH1A1NPSR1IDO1TSHRNPC1
SCHEMBL17254235 0.76 KDM4E (0.46) ALDH1A1NPSR1IDO1TSHRNPC1
SCHEMBL8181746 0.76 CTSD (0.44) RAB9ASMN1; SMN2KDM4EKMT2ACTSD
SCHEMBL3925721 0.76 SOAT2 (0.47) ALDH1A1NPSR1GAAKMT2A
SCHEMBL8542456 0.75 ALDH1A1 (0.48) ALDH1A1NPSR1IDO1TSHRNPC1
SCHEMBL11328122 0.75 ALDH1A1 (0.54) ALDH1A1NPSR1IDO1TSHRNPC1
SCHEMBL5073196 0.74 SOAT2 (0.50) ALDH1A1NPSR1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 729 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116240753-B Lasting fragrance-releasing adhesive film paper with sleep-aiding effect for artificial board veneers 浙江升华云峰新材股份有限公司 2024-05-03 CN claimed
WO-2024091736-A2 LONG WEAR NON-CRACKING COLOR COSMETIC COMPOSITIONS REVLON CONSUMER PRODUCTS LLC (US) 2024-05-02 WO claimed
CN-116240753-A Lasting fragrance-releasing adhesive film paper with sleep-aiding effect for artificial board veneers 浙江升华云峰新材股份有限公司 2023-06-09 CN claimed
CN-115044203-A Low-dielectric high-temperature-resistant resin-based composite material and preparation method thereof 中电科芜湖钻石飞机制造有限公司 2022-09-13 CN claimed
CN-114920861-A Catalyst and preparation method thereof, and preparation method of TPX polymer 宁夏清研高分子新材料有限公司 2022-08-19 CN claimed
CN-114874365-A Catalyst of TPX polymer and preparation method and application thereof 宁夏清研高分子新材料有限公司 2022-08-09 CN claimed
CN-114835902-A POSS (polyhedral oligomeric silsesquioxane) -based flame retardant containing phosphorus, nitrogen and silicon elements and preparation method thereof 江南大学 2022-08-02 CN claimed
CN-114369215-A Hybrid phenolic resin, synthetic method thereof and fiber/hybrid phenolic resin composite material 西北工业大学 2022-04-19 CN claimed
US-10752503-B2 Spherical boron nitride fine powder, method for manufacturing same and thermally conductive resin composition using same DENKA COMPANY LIMITED (JP) 2020-08-25 US claimed
US-10273048-B2 Delamination resistant glass containers with heat-tolerant coatings CORNING INCORPORATED (US) 2019-04-30 US claimed
US-20030199620-A1 Composition for forming overcoat layer for organic photoreceptor and organic photoreceptor employing overcoat layer prepared from the composition SAMSUNG ELECTRONICS CO., LTD. OF REPUBLIC OF KOREA (KR) 2003-10-23 US claimed
US-20030195283-A1 Composition for forming overcoat layer for organic photoreceptor and organic photoreceptor employing overcoat layer prepared from the composition SAMSUNG ELECTRONICS CO., LTD. (KR) 2003-10-16 US claimed
EP-1304345-A2 Aminoalkylalkoxysiloxan containing mixtures , their preparation process and their use Degussa AG (DE) 2003-04-23 EP claimed
US-20030072873-A1 Aminoalkylalkoxysiloxane mixtures DEGUSSA AG (DE) 2003-04-17 US claimed
US-6395858-B1 AMINOALKYLSILANOL AND SIMILAR COMPOUNDS DEGUSSA AG (DE) 2002-05-28 US claimed
US-5948419-A AQUEOUS EMULSION POLYMERIC BINDER; SILANE COUPLING AGENT THE DUMAIS COMPANIES, L.L.C. (US) 1999-09-07 US claimed
WO-1999033432-A1 AQUEOUS-BASED NAIL COATING COMPOSITION THE DUMAIS COMPANIES, L.L.C. (US) 1999-07-08 WO claimed
EP-0828718-A1 HETEROCYCLO SUBSTITUTED HYDROXAMIC ACID DERIVATIVES AS CYCLOOXYGENASE-2 AND 5-LIPOXYGENASE INHIBITORS G.D. SEARLE & CO. (US) 1998-03-18 EP claimed
WO-1996038418-A1 HETEROCYCLO SUBSTITUTED HYDROXAMIC ACID DERIVATIVES AS CYCLOOXYGENASE-2 AND 5-LIPOXYGENASE INHIBITORS G.D. SEARLE & CO. (US) 1996-12-05 WO claimed
US-5235005-A Containing organosilicon compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-08-10 US claimed