Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CTH | P32929 | 1/20 | 0.33 |
| ▸ | CBS | P35520 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4478714 | 0.90 | ALDH1A1 (0.33) | TSHRALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL4479756 | 0.84 | TAS2R38 (0.39) | TSHRALDH1A1POLBKMT2ACTH | |
| SCHEMBL4977502 | 0.81 | TSHR (0.37) | TSHRALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL4978322 | 0.77 | TSHR (0.35) | TSHRALDH1A1POLBKMT2ACTH | |
| SCHEMBL4472825 | 0.77 | TSHR (0.39) | TSHRALDH1A1POLBKMT2ACTH | |
| SCHEMBL4488898 | 0.76 | KDM4E (0.34) | TSHRALDH1A1POLBKMT2ACTH | |
| SCHEMBL4467707 | 0.74 | TSHR (0.36) | TSHRALDH1A1POLBKMT2ACTH | |
| SCHEMBL26928 | 0.74 | — | — | |
| SCHEMBL11406963 | 0.73 | FOLH1 (0.46) | TSHRPOLBCTHCBSTHPO | |
| SCHEMBL4472021 | 0.72 | TSHR (0.33) | TSHRALDH1A1POLBKMT2ACTH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685114-B1 | ANTIBACTERIAL AND/OR ANTIPROTOZOAL NITROIMIDAZOLE DERIVATIVE COMPOUNDS WITH UREASE INHIBITOR ACTIVITY, PROCESS FOR PREPARING THESE COMPOUNDS AND USE IN PHARMACEUTICAL COMPOSITIONS AND MEDICINES. | EMS SA (BR) | 2008-10-15 | — | — | EP | claimed |