SCHEMBL4977201

SCHEMBL4977201

CCNc1ccc(S)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.48
ADRA2A P08913 7/20 0.47
ADRA2B P18089 3/20 0.47
ADRA2C P18825 3/20 0.47
LMNA P02545 1/20 0.47
GAA P10253 2/20 0.34
ALDH1A1 P00352 2/20 0.33
POLB P06746 2/20 0.33
HPGD P15428 2/20 0.33
CASP1 P29466 2/20 0.33
HSD17B10 Q99714 2/20 0.33
IDO1 P14902 2/20 0.33
KDM4E B2RXH2 1/20 0.33
RECQL P46063 1/20 0.33
CASP7 P55210 1/20 0.33
MEN1 O00255 1/20 0.33
APAF1 O14727 1/20 0.33
USP2 O75604 1/20 0.33
ALOX15 P16050 1/20 0.33
ALOX12 P18054 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL526383 0.86 MAPT (0.58) MAPTADRA2AADRA2BADRA2CLMNA
Hydrochloric Acid SCHEMBL9181167 0.83 MAPT (0.56) MAPTADRA2AADRA2BADRA2CLMNA
SCHEMBL4976072 0.80 MAPT (0.46) MAPTGAAALDH1A1IDO1MEN1
SCHEMBL27885803 0.79 MAPT (0.48) MAPTADRA2AADRA2BADRA2CLMNA
SCHEMBL8329203 0.79 MAPT (0.48) MAPTADRA2AADRA2BADRA2CLMNA
SCHEMBL11544937 0.78 LMNA (0.56) MAPTADRA2AADRA2BADRA2CLMNA
SCHEMBL7012895 0.78 LMNA (0.56) MAPTADRA2AADRA2BADRA2CLMNA
SCHEMBL6032298 0.77 MAPT (0.43) MAPTADRA2BLMNAGAAALDH1A1
SCHEMBL247849 0.76 MAPT (0.67) MAPTADRA2AADRA2BADRA2CLMNA
SCHEMBL7208976 0.76 MAPT (0.50) MAPTADRA2AADRA2BADRA2CLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11560422-B2 Sulfonamide-containing linkage systems for drug conjugates ZYMEWORKS INC. 2023-01-24 US disclosed
EP-2933875-B1 PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL COMPLEX DYE, DYE SOLUTION, DYE-ADSORBED ELECTRODE, AND METHOD FOR PRODUCING DYE-SENSITIZED SOLAR CELL FUJIFILM CORP (JP) 2017-03-29 EP disclosed
US-20170029490-A1 SULFONAMIDE-CONTAINING LINKAGE SYSTEMS FOR DRUG CONJUGATES ZYMEWORKS INC. (CA) 2017-02-02 US disclosed
US-7332261-B2 Phthalocyanine compound, process for preparing the same, and optical recording medium containing the same CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-02-19 US disclosed
EP-1482013-B1 PHTHALOCYANINE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND OPTICAL RECORDING MEDIUM CONTAINING THE SAME CIBA SC HOLDING AG (CH) 2007-07-18 EP disclosed
US-20050201265-A1 Phthalocyanine compound, process for producing the same, and optical recording medium containing the same MITSUI CHEMICALS, INC. (JP) 2005-09-15 US disclosed
EP-1482013-A1 PHTHALOCYANINE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND OPTICAL RECORDING MEDIUM CONTAINING THE SAME MITSUI CHEMICALS, INC. (JP) 2004-12-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11560422-B2 Sulfonamide-containing linkage systems for drug conjugates MPST, TPST2, SULT1A1 MAPT 212/4885ADRA2A 3941/4885ADRA2B 4259/4885
US-20170029490-A1 SULFONAMIDE-CONTAINING LINKAGE SYSTEMS FOR DRUG CONJUGATES MPST, TPST2, SULT1A1 MAPT 212/4885ADRA2A 3941/4885ADRA2B 4259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.