Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16415482 | 0.90 | OPRM1 (0.32) | OPRM1OPRL1 | |
| SCHEMBL16416213 | 0.85 | OPRM1 (0.32) | OPRM1OPRL1 | |
| SCHEMBL23528023 | 0.80 | CA12 (0.33) | OPRM1OPRL1 | |
| SCHEMBL2798365 | 0.77 | USP2 (0.43) | — | |
| SCHEMBL16914443 | 0.76 | OPRM1 (0.30) | OPRM1OPRL1 | |
| SCHEMBL1818822 | 0.76 | HSD11B1 (0.39) | OPRM1OPRL1 | |
| SCHEMBL23270082 | 0.76 | — | — | |
| SCHEMBL5497668 | 0.76 | CA12 (0.32) | — | |
| SCHEMBL2202122 | 0.75 | NPC1 (0.33) | — | |
| SCHEMBL16914465 | 0.73 | OPRM1 (0.36) | OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080021038-A1 | Novel Piperidine/8-Azabicyclo [3.2.1.] Octan Derivatives As Modulators Of Chemokine Receptor Ccr5 | TUCKER HOWARD | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021038-A1 | Novel Piperidine/8-Azabicyclo [3.2.1.] Octan Derivatives As Modulators Of Chemokine Receptor Ccr5 | CCR5, CXCR1, CCR2 | OPRM1 31/4885OPRL1 64/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.