SCHEMBL497740

SCHEMBL497740

Oc1ccccc1COP(O)OCl

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.50
HSPA5 P11021 1/20 0.43
KEAP1 Q14145 1/20 0.40
TSHR P16473 2/20 0.39
CYP2D6 P10635 1/20 0.39
HIF1A Q16665 1/20 0.39
TAAR1 Q96RJ0 1/20 0.38
AKR1B1 P15121 1/20 0.38
CA12 O43570 4/20 0.37
CA2 P00918 4/20 0.37
CA9 Q16790 3/20 0.36
MPO P05164 1/20 0.36
APP P05067 1/20 0.36
KDM4E B2RXH2 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL185875 0.81 IDO1 (0.53) IDO1HSPA5KEAP1TSHRCYP2D6
SCHEMBL3507942 0.80 IDO1 (0.57) IDO1HSPA5KEAP1TSHRCYP2D6
SCHEMBL185874 0.79 IDO1 (0.55) IDO1HSPA5KEAP1TSHRCYP2D6
SCHEMBL3507940 0.78 IDO1 (0.59) IDO1HSPA5KEAP1TSHRCYP2D6
SCHEMBL11791488 0.76 IDO1 (0.61) IDO1HSPA5KEAP1TSHRCYP2D6
SCHEMBL28546168 0.75 TSHR (0.44) IDO1TSHRHIF1ACA12CA2
SCHEMBL29152360 0.72 IDO1 (0.52) IDO1HSPA5KEAP1TSHRCYP2D6
SCHEMBL126999 0.71 IDO1 (0.67) IDO1HSPA5KEAP1TSHRCYP2D6
SCHEMBL17766315 0.71 IDO1 (0.39) IDO1HSPA5KEAP1TSHRCYP2D6
SCHEMBL30434974 0.69 IDO1 (0.53) IDO1HSPA5KEAP1TSHRCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4683927-A1 ALPHA-MODIFIED NUCLEOSIDE TRIPHOSPHATES AND METHOD FOR THEIR SYNTHESIS Illumina, Inc. (US) 2026-01-28 EP claimed
WO-2024196883-A1 ALPHA-MODIFIED NUCLEOSIDE TRIPHOSPHATES AND METHOD FOR THEIR SYNTHESIS ILLUMINA, INC. (US) 2024-09-26 WO claimed
EP-3110825-B1 NOVEL SYNTHETIC OLIGOMERS OF NEISSERIA MENINGITIS SEROGROUP X AND PROCESS OF PREPARING THEM MSD WELLCOME TRUST HILLEMAN LABORATORIES PVT LTD (IN) 2020-12-09 EP claimed
CN-106061986-B Novel synthetic oligomers of neisseria meningitidis serogroup X and process for their preparation 默沙东和惠康基金会合资的希勒曼实验室私人有限公司 2020-07-07 CN claimed
US-10183962-B2 Synthetic oligomers of Neisseria meningitis serogroup X and process of preparing them MSD WELLCOME TRUST HILLEMAN LABORATORIES PVT. LTD. (IN) 2019-01-22 US claimed
US-20170066794-A1 NOVEL SYNTHETIC OLIGOMERS OF NEISSERIA MENINGITIS SEROGROUP X AND PROCESS OF PREPARING THEM MSD WELLCOME TRUST HILLEMAN LABORATORIES PVT. LTD. (IN) 2017-03-09 US claimed
EP-3110825-A1 NOVEL SYNTHETIC OLIGOMERS OF NEISSERIA MENINGITIS SEROGROUP X AND PROCESS OF PREPARING THEM Msd Wellcome Trust Hilleman Laboratories Pvt. Ltd. (IN) 2017-01-04 EP claimed
WO-2015128797-A1 NOVEL SYNTHETIC OLIGOMERS OF NEISSERIA MENINGITIS SEROGROUP X AND PROCESS OF PREPARING THEM MSD WELLCOME TRUST HILLEMAN LABORATORIES PVT. LTD. (IN) 2015-09-03 WO claimed
EP-4683927-A1 ALPHA-MODIFIED NUCLEOSIDE TRIPHOSPHATES AND METHOD FOR THEIR SYNTHESIS Illumina, Inc. (US) 2026-01-28 EP disclosed
US-20250361260-A1 NUCLEOTIDE ANALOGUES SINGULAR GENOMICS SYSTEMS INC (US) 2025-11-27 US disclosed
US-20250346950-A1 TAGGED NUCLEOSIDE COMPOUNDS USEFUL FOR NANOPORE DETECTION Roche Sequencing Solutions, Inc. (US) 2025-11-13 US disclosed
US-12270075-B2 Tagged nucleoside compounds useful for nanopore detection Roche Sequencing Solutions, Inc. (US) 2025-04-08 US disclosed
US-12215122-B2 Nucleotide analogues Singular Genomics Systems, Inc. (US) 2025-02-04 US disclosed
US-12195493-B2 Reversibly blocked nucleoside analogues and their use MGI TECH CO., LTD. (CN) 2025-01-14 US disclosed
US-5204455-A Monomethoxytrityl protected oligonucleotides bound to a solid support ISIS PHARMACEUTICALS, INC. 1993-04-20 US disclosed
US-5164491-A Large scale synthesis of oligonucleotides and their associated analogs GILEAD SCIENCES (US) 1992-11-17 US disclosed
EP-0241363-B1 NUCLEOSIDE DERIVATIVES AND THEIR USE IN THE SYNTHESIS OF OLIGONUCLEOTIDES COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1991-09-25 EP disclosed
EP-0438203-A2 Nucleoside derivatives and their use in oligonucleotide synthesis COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1991-07-24 EP disclosed
US-4980460-A Protected nucleosides which permit more efficient oligonucleotide syntheses COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1990-12-25 US disclosed
EP-0241363-A1 Nucleoside derivatives and their use in the synthesis of oligonucleotides COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1987-10-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250346950-A1 TAGGED NUCLEOSIDE COMPOUNDS USEFUL FOR NANOPORE DETECTION PNP, NT5C3B, POLN IDO1 4654/4885HSPA5 4590/4885KEAP1 4679/4885
US-12270075-B2 Tagged nucleoside compounds useful for nanopore detection NT5C3B, PNP, POLN IDO1 4688/4885HSPA5 4473/4885KEAP1 4697/4885
US-12215122-B2 Nucleotide analogues NUDT1, POLN, TYMP IDO1 3909/4885HSPA5 2564/4885KEAP1 4512/4885
US-20170066794-A1 NOVEL SYNTHETIC OLIGOMERS OF NEISSERIA MENINGITIS SEROGROUP X AND PROCESS OF PREPARING THEM MLEC, MEN1, MAN2B2 IDO1 2127/4885HSPA5 4480/4885KEAP1 1563/4885
US-12195493-B2 Reversibly blocked nucleoside analogues and their use NSUN2, NME2, ADAR IDO1 4829/4885HSPA5 2216/4885KEAP1 4831/4885
US-20250361260-A1 NUCLEOTIDE ANALOGUES ADAR, NUDT1, NSUN2 IDO1 4209/4885HSPA5 2909/4885KEAP1 4579/4885
US-10183962-B2 Synthetic oligomers of Neisseria meningitis serogroup X and process of preparing them MLEC, MEN1, MAN2B2 IDO1 1749/4885HSPA5 4411/4885KEAP1 1146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.