SCHEMBL4977841

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL737308	0.84	SLC40A1 (0.48)	KMT2AHSD17B10KDM4EALDH1A1HPGD
	SCHEMBL27711752	0.83	SLC40A1 (0.47)	KMT2AKDM4EALDH1A1MEN1SLC40A1
	SCHEMBL739704	0.83	KDM4E (0.53)	KMT2AHSD17B10KDM4EALDH1A1HPGD
	SCHEMBL8636736	0.81	IDO1 (0.46)	ALDH1A1
	SCHEMBL27975877	0.80	MAPT (0.43)	KMT2AKDM4EALDH1A1MEN1SLC40A1
	SCHEMBL12566146	0.80	COMT (0.52)	KMT2AKDM4EALDH1A1HPGDMEN1
	SCHEMBL12599627	0.79	CKS1B (0.44)	PDE4APDE4CPDE4D
	SCHEMBL3615001	0.79	MAPT (0.52)	KMT2AKDM4EALDH1A1GAAMEN1
	SCHEMBL23292188	0.78	PDE4A (0.42)	KDM4EALDH1A1SLC40A1PDE4APDE4C
	SCHEMBL1506959	0.78	HTR1A (0.53)	KMT2AHSD17B10KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.