Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29626748 | 0.83 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1ALDH1A1PRMT6KDM4E | |
| SCHEMBL180808 | 0.83 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1ALDH1A1PRMT6KDM4E | |
| SCHEMBL6293989 | 0.76 | NOS3 (0.34) | HSP90AA1HSP90AB1NOS3NOS1NOS2 | |
| SCHEMBL2068476 | 0.73 | SMN1; SMN2 (0.32) | SMN1; SMN2NOS3NOS1NOS2 | |
| SCHEMBL1831943 | 0.68 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL3257531 | 0.68 | ALDH1A1 (0.37) | SMN1; SMN2HSP90AA1ALDH1A1KDM4E | |
| SCHEMBL29686176 | 0.67 | — | — | |
| SCHEMBL2067821 | 0.67 | — | — | |
| SCHEMBL1653770 | 0.66 | — | — | |
| SCHEMBL31105996 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080045727-A1 | Chiral 3-Halophthalic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2008-02-21 | — | — | US | disclosed |
| EP-1789383-A1 | CHIRAL 3-HALOPHTHALIC ACID DERIVATIVES | Bayer CropScience AG (DE) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006024402-A1 | CHIRAL 3-HALOPHTHALIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2006-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045727-A1 | Chiral 3-Halophthalic Acid Derivatives | HDHD5, CRYZ, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | SMN1; SMN2 4855/4885HSP90AA1 867/4885HSP90AB1 1289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.