Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 6/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4196108 | 0.91 | ITGB3 (0.35) | ITGB3ITGA2BELANEACHE | |
| SCHEMBL4198742 | 0.76 | KMT2A (0.35) | HRH4HRH3ACHE | |
| SCHEMBL4192563 | 0.75 | KMT2A (0.34) | HRH4HRH3ACHE | |
| SCHEMBL4669848 | 0.57 | ACHE (0.57) | ACHE | |
| SCHEMBL30357422 | 0.56 | EPHX1 (0.42) | ACHE | |
| SCHEMBL10440897 | 0.56 | NPC1 (0.57) | ACHE | |
| SCHEMBL19331815 | 0.56 | NPC1 (0.57) | ACHE | |
| SCHEMBL3975468 | 0.56 | ACHE (0.88) | ACHE | |
| SCHEMBL7569673 | 0.56 | ACHE (0.81) | ACHE | |
| SCHEMBL10939707 | 0.56 | ACHE (0.81) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1994035-A1 | CEPHEM COMPOUNDS AND USE AS ANTIMICROBIAL AGENTS | Astellas Pharma Inc. (JP) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007119511-A1 | CEPHEM COMPOUNDS AND USE AS ANTIMICROBIAL AGENTS | ASTELLAS PHARMA INC. (JP) | 2007-10-25 | — | — | WO | disclosed |