SCHEMBL497956

SCHEMBL497956

C=CCc1cc2ccccc2c(C(=O)O)c1CC=C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
ALDH1A1 P00352 3/20 0.53
HPGD P15428 2/20 0.53
CYP1A2 P05177 2/20 0.53
KDM4E B2RXH2 2/20 0.53
GLA P06280 1/20 0.53
CYP2C19 P33261 1/20 0.53
HSD17B10 Q99714 1/20 0.53
ME2 P23368 1/20 0.49
ME1 P48163 1/20 0.49
ME3 Q16798 1/20 0.49
GPR35 Q9HC97 2/20 0.40
POLB P06746 2/20 0.40
MAPT P10636 1/20 0.37
CYP3A4 P08684 1/20 0.36
STAT6 P42226 1/20 0.36
HIF1A Q16665 1/20 0.36
PTPN1 P18031 1/20 0.36
CDC25B P30305 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2880041 0.88 MEN1 (0.56) MEN1KMT2AALDH1A1HPGDCYP1A2
SCHEMBL7396868 0.87 ME2 (0.57) MEN1KMT2AALDH1A1HPGDCYP1A2
SCHEMBL7378328 0.84 MEN1 (0.51) MEN1KMT2AALDH1A1HPGDCYP1A2
SCHEMBL9741180 0.82 ME2 (0.49) MEN1KMT2AALDH1A1HPGDCYP1A2
SCHEMBL4591157 0.81 MEN1 (0.51) MEN1KMT2AALDH1A1HPGDCYP1A2
SCHEMBL487677 0.80 KDM4E (0.49) MEN1KMT2AALDH1A1HPGDCYP1A2
SCHEMBL11236463 0.79 GPR35 (0.54) MEN1KMT2AALDH1A1HPGDCYP1A2
SCHEMBL5138488 0.79 HTR2A (0.42) MEN1KMT2AALDH1A1HPGDKDM4E
SCHEMBL497955 0.79 ALDH1A1 (0.42) MEN1KMT2AALDH1A1HPGDCYP1A2
SCHEMBL27829330 0.79 PTPN1 (0.45) MEN1KMT2AALDH1A1HPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2350182-A1 METHOD OF QUENCHING ELECTRONIC EXCITATION OF CHROMOPHORE-CONTAINING ORGANIC MOLECULES IN PHOTOACTIVE COMPOSITIONS HallStar Innovations Corp. (US) 2011-08-03 EP claimed
US-7959834-B2 Alkoxycrylene/metal oxide photostabilized photoactive compositions and methods HALLSTAR INNOVATIONS CORP. (US) 2011-06-14 US claimed
US-20100283015-A1 Alkoxycrylene/Metal Oxide Photostabilized Photoactive Compositions and Methods HALLSTAR INNOVATIONS CORP. (US) 2010-11-11 US claimed
US-7754191-B2 Method of quenching electronic excitation of chromophore-containing organic molecules photoactive compositions HALLSTAR INNOVATIONS CORP. (US) 2010-07-13 US claimed
WO-2010051103-A1 METHOD OF QUENCHING ELECTRONIC EXCITATION OF CHROMOPHORE-CONTAINING ORGANIC MOLECULES IN PHOTOACTIVE COMPOSITIONS HALLSTAR INNOVATIONS CORP. (US) 2010-05-06 WO claimed
US-20090057627-A1 Method of quenching electronic excitation of chromophore-containing organic molecules photoactive compositions HALLSTAR INNOVATIONS CORP. (US) 2009-03-05 US claimed
EP-1633463-B1 PROCESS FOR FORMING AN EMULSION USING MICROCHANNEL PROCESS TECHNOLOGY VELOCYS INC (US) 2007-10-24 EP claimed
EP-1127568-B1 Cosmetic and dermatological light protective formulations containing benzotriazole derivatives and alkylnaphthalates BEIERSDORF AG (DE) 2007-01-24 EP claimed
EP-0232605-B1 PRESSURE VESSELS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-09-19 EP claimed
EP-3812414-A1 HIGH IV MELT PHASE POLYESTER POLYMER CATALYZED WITH ANTIMONY CONTAINING COMPOUNDS GRUPO PETROTEMEX, S.A. DE C.V. (MX) 2021-04-28 EP disclosed
EP-2518096-B1 HIGH IV MELT PHASE POLYESTER POLYMER CATALYZED WITH ANTIMONY CONTAINING COMPOUNDS GRUPO PETROTEMEX SA DE CV (MX) 2021-04-21 EP disclosed
US-10370486-B2 Polyester polymer particles having a small surface to center molecular weight gradient GRUPO PETROTEMEX S.A. DE C.V. (MX) 2019-08-06 US disclosed
EP-2052007-B1 MULTIPLE FEEDS OF CATALYST METALS TO A POLYESTER PRODUCTION PROCESS GRUPO PETROTEMEX SA DE CV (MX) 2018-03-28 EP disclosed
EP-1784440-B1 REMOVAL OF RESIDUAL ACETALDEHYDE FROM POLYESTER POLYMER PARTICLES GRUPO PETROTEMEX SA DE CV (MX) 2018-01-10 EP disclosed
WO-2003020317-A2 COSMETIC AND DERMATOLOGICAL LIGHT-PROTECTIVE FORMULATION WITH A CONTENT OF WATER-SOLUBLE UV-FILTER SUBSTANCES AND ALKYLNAPHTHALATES BEIERSDORF AG (DE) 2003-03-13 WO disclosed
EP-1129696-A2 Stabilisation of oxidation- and/or UV-sensitive compounds Beiersdorf AG (DE) 2001-09-05 EP disclosed
EP-1127569-A2 Cosmetic and dermatological light protective formulations containing asymmetrically substituted triazine derivatives and alkylnaphthalates Beiersdorf AG (DE) 2001-08-29 EP disclosed
EP-1127568-A2 Cosmetic and dermatological light protective formulations containing benzotriazole derivatives and alkylnaphthalates Beiersdorf AG (DE) 2001-08-29 EP disclosed
EP-0308745-B1 THICKENED MOULDING COMPOSITION BASF Aktiengesellschaft (DE) 1992-11-19 EP disclosed
EP-0308745-A2 Thickened moulding composition BASF Aktiengesellschaft (DE) 1989-03-29 EP disclosed