Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Ethylene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3749811 | 0.96 | GPR3 (0.34) | GPR3 | |
| Hydrochloric Acid SCHEMBL29912111 | 0.96 | GPR3 (0.34) | GPR3 | |
| Hydrochloric Acid SCHEMBL30338176 | 0.96 | GPR3 (0.34) | GPR3 | |
| Hydrochloric Acid SCHEMBL28331194 | 0.81 | BCHE (0.30) | — | |
| Hydrochloric Acid SCHEMBL30798590 | 0.81 | GPR3 (0.32) | GPR3 | |
| Ethylene SCHEMBL6914332 | 0.79 | GPR3 (0.39) | GPR3 | |
| Hydrochloric Acid SCHEMBL5691746 | 0.78 | GPR3 (0.31) | GPR3 | |
| Ethane SCHEMBL8163438 | 0.74 | GPR3 (0.44) | GPR3 | |
| Hydrochloric Acid SCHEMBL7199527 | 0.74 | ADRA2A (0.32) | GPR3 | |
| Hydrochloric Acid SCHEMBL7199222 | 0.74 | BCHE (0.32) | GPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051536-A1 | Method for Producing (Co) Polymer Having Carboxyl Group | JSR CORPORATION (JP) | 2008-02-28 | — | — | US | disclosed |
| EP-1770104-A1 | METHOD FOR PRODUCING (CO)POLYMER HAVING CARBOXYL GROUP | JSR Corporation (JP) | 2007-04-04 | — | — | EP | disclosed |
| EP-0530908-B2 | Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins | DSM NV (NL) | 2003-06-04 | — | — | EP | disclosed |
| EP-0530908-B1 | Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins | DSM NV (NL) | 1999-04-21 | — | — | EP | disclosed |
| US-5646083-A | Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins | DSM N.V. (NL) | 1997-07-08 | — | — | US | disclosed |
| EP-0530908-A1 | Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins | DSM N.V. (NL) | 1993-03-10 | — | — | EP | disclosed |