Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.61 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31758199 | 0.94 | CES1 (0.59) | CES1CES2TSHRDAONAPRT | |
| SCHEMBL8797871 | 0.92 | CES1 (0.57) | CES1CES2TSHRDAONAPRT | |
| SCHEMBL1056586 | 0.86 | CES1 (0.67) | CES1CES2TSHRDAONAPRT | |
| Benzoic Acid SCHEMBL28183938 | 0.79 | TSHR (0.56) | CES1CES2TSHRDAONAPRT | |
| SCHEMBL11982629 | 0.79 | CA2 (0.63) | CES1CES2ALDH1A1HDAC1HDAC7 | |
| SCHEMBL10528373 | 0.77 | CES1 (0.67) | CES1CES2TSHRDAONAPRT | |
| Perflubutane SCHEMBL28615208 | 0.77 | TSHR (0.67) | CES1CES2TSHRDAONAPRT | |
| Perflutren SCHEMBL28607914 | 0.77 | TSHR (0.67) | CES1CES2TSHRDAONAPRT | |
| SCHEMBL33083 | 0.77 | CES1 (1.00) | CES1CES2TSHRDAONAPRT | |
| SCHEMBL7907262 | 0.77 | CES1 (0.73) | CES1CES2TSHRDAONAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3037455-B1 | METHOD FOR SEPARATING CARBOXYLIC ACID COMPOUND CONTAINING PERFLUORO(POLY)ETHER GROUP | DAIKIN IND LTD (JP) | 2018-10-31 | — | — | EP | disclosed |
| EP-3351250-A2 | PHOSPHATE MANAGEMENT WITH SMALL MOLECULES | Opko Ireland Global Holdings, Ltd. (IE) | 2018-07-25 | — | — | EP | disclosed |
| EP-3251677-A2 | PHOSPHATE MANAGEMENT WITH SMALL MOLECULES | OPKO Ireland Global Holdings, Limited (IE) | 2017-12-06 | — | — | EP | disclosed |
| EP-2389183-B1 | PHOSPHATE MANAGEMENT WITH SMALL MOLECULES | OPKO IRELAND GLOBAL HOLDINGS LTD (IE) | 2017-05-31 | — | — | EP | disclosed |
| EP-3037455-A1 | METHOD FOR SEPARATING CARBOXYLIC ACID COMPOUND CONTAINING PERFLUORO(POLY)ETHER GROUP | Daikin Industries, Ltd. (JP) | 2016-06-29 | — | — | EP | disclosed |
| US-9198923-B2 | Phosphate management with small molecules | Opko Ireland Global Holdings, Ltd. (KY) | 2015-12-01 | — | — | US | disclosed |
| US-9198923-B2 | Phosphate management with small molecules | Opko Ireland Global Holdings, Ltd. (KY) | 2015-12-01 | — | — | US | disclosed |
| US-20120028926-A1 | Phosphate Management with Small Molecules | CYTOCHROMA INC. (CA) | 2012-02-02 | — | — | US | disclosed |
| US-20120028926-A1 | Phosphate Management with Small Molecules | CYTOCHROMA INC. (CA) | 2012-02-02 | — | — | US | disclosed |
| US-8106222-B2 | Fluorine-containing ether compound | FUJIFILM CORPORATION (JP) | 2012-01-31 | — | — | US | disclosed |
| US-6261738-B1 | LATENT CURING CATALYSTS FOR PHOTORESISTS SUCH AS 2,2,2-TRIFLUORO-1-PHENYL-ETHANONE OXIME-O-METHYL SULFONATE | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-07-17 | — | — | US | disclosed |
| EP-0458201-B1 | 9,9-Bis(perfluoroalkyl)xanthene 9-aryl-9-perfluoroalkylxanthene, monomers and polymers derived therefrom | DU PONT (US) | 1997-08-27 | — | — | EP | disclosed |
| US-5202446-A | Used in preperation of polyimides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-04-13 | — | — | US | disclosed |
| US-5189138-A | COMPOUNDS, MONOMERS, AND POLYMERS BASED ON PERFLUOROALKYL AND PERFLUOROALKYL-ARYL DIOXAPENTACENE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-02-23 | — | — | US | disclosed |
| US-5153336-A | Chemical intermediates for polyimides; rigid, low dielectric, waterproofing; electronic packaging | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0500026-A1 | Compounds, monomers, and polymers based on perfluoroalkyl and perfluoroalkyl-aryl dioxapentacene | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-08-26 | — | — | EP | disclosed |
| US-5101004-A | Packaging electronic apparatus | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-03-31 | — | — | US | disclosed |
| US-5097000-A | Polyimides, packaging for electronic equipment | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-03-17 | — | — | US | disclosed |
| EP-0458201-A2 | 9,9-Bis(perfluoroalkyl)xanthene 9-aryl-9-perfluoroalkylxanthene, monomers and polymers derived therefrom | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-11-27 | — | — | EP | disclosed |
| US-5051520-A | Chemical intermediates for polymers such as polyimides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028926-A1 | Phosphate Management with Small Molecules | SLC34A2, PHPT1, SLC34A3 | CES1 1535/4885CES2 3144/4885TSHR 2366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.