Sugi Predict

Sugi Predict / Compounds / SCHEMBL498122

SCHEMBL498122

SCHEMBL498122

NC(N)(CCCCCC(=O)O)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 5/20 0.55
▸ LMNA P02545 3/20 0.55
▸ NFKB1 P19838 2/20 0.55
▸ PMP22 Q01453 1/20 0.55
▸ ALDH1A1 P00352 3/20 0.50
▸ MEN1 O00255 2/20 0.50
▸ ALOX15 P16050 2/20 0.50
▸ KMT2A Q03164 2/20 0.50
▸ PLG P00747 1/20 0.50
▸ THRB P10828 1/20 0.50
▸ SLC6A2 P23975 1/20 0.50
▸ RECQL P46063 1/20 0.50
▸ SLC6A3 Q01959 1/20 0.50
▸ GPR84 Q9NQS5 8/20 0.46
▸ FFAR1 O14842 2/20 0.46
▸ FFAR4 Q5NUL3 2/20 0.46
▸ CYP2D6 P10635 1/20 0.46
▸ PPARG P37231 6/20 0.44
▸ PPARD Q03181 6/20 0.44
▸ PPARA Q07869 6/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28977817 1.00 TSHR (0.55) TSHRLMNANFKB1PMP22ALDH1A1
SCHEMBL497446 1.00 TSHR (0.55) TSHRLMNANFKB1PMP22ALDH1A1
SCHEMBL31009783 1.00 TSHR (0.55) TSHRLMNANFKB1PMP22ALDH1A1
SCHEMBL7771205 1.00 TSHR (0.55) TSHRLMNANFKB1PMP22ALDH1A1
Pimelic Acid SCHEMBL18600626 1.00 TSHR (0.55) TSHRLMNANFKB1PMP22ALDH1A1
Hydrochloric Acid SCHEMBL27405461 0.98 TSHR (0.52) TSHRLMNANFKB1PMP22ALDH1A1
SCHEMBL27739960 0.98 LMNA (0.52) TSHRLMNANFKB1PMP22ALDH1A1
SCHEMBL29290 0.98 LMNA (0.52) TSHRLMNANFKB1PMP22ALDH1A1
Ammonia Solution, Strong SCHEMBL28096291 0.95 LMNA (0.50) TSHRLMNANFKB1PMP22ALDH1A1
SCHEMBL27555394 0.95 LMNA (0.50) TSHRLMNANFKB1PMP22ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 318 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12576169-B2 Silicon-fluoride acceptor substituted radiopharmaceuticals and precursors thereof Technische Universität München (DE) 2026-03-17 — — US claimed
CN-117801204-A Bio-based hydrolysis-resistant elastomer, preparation method and application thereof 万华化学集团股份有限公司 2024-04-02 — — CN claimed
US-20220096669-A1 SILICON-FLUORIDE ACCEPTOR SUBSTITUTED RADIOPHARMACEUTICALS AND PRECURSORS THEREOF Technische Universität München (DE) 2022-03-31 — — US claimed
EP-3917581-A1 SILICON-FLUORIDE ACCEPTOR SUBSTITUTED RADIOPHARMACEUTICALS AND PRECURSORS THEREOF Technische Universität München (DE) 2021-12-08 — — EP claimed
WO-2020157128-A1 SILICON-FLUORIDE ACCEPTOR SUBSTITUTED RADIOPHARMACEUTICALS AND PRECURSORS THEREOF Technische Universität München (DE) 2020-08-06 — — WO claimed
JP-63027499-A — — None — — JP disclosed
US-12576169-B2 Silicon-fluoride acceptor substituted radiopharmaceuticals and precursors thereof Technische Universität München (DE) 2026-03-17 — — US disclosed
CN-113677375-B Silicon fluoride receptor substituted radiopharmaceuticals and precursors thereof 慕尼黑工业大学 2024-07-23 — — CN disclosed
CN-117801204-A Bio-based hydrolysis-resistant elastomer, preparation method and application thereof 万华化学集团股份有限公司 2024-04-02 — — CN disclosed
US-20220096669-A1 SILICON-FLUORIDE ACCEPTOR SUBSTITUTED RADIOPHARMACEUTICALS AND PRECURSORS THEREOF Technische Universität München (DE) 2022-03-31 — — US disclosed
EP-3917581-A1 SILICON-FLUORIDE ACCEPTOR SUBSTITUTED RADIOPHARMACEUTICALS AND PRECURSORS THEREOF Technische Universität München (DE) 2021-12-08 — — EP disclosed
US-10759748-B2 Compounds as L-cystine crystallization inhibitors and uses thereof NEW YORK UNIVERSITY (US) 2020-09-01 — — US disclosed
WO-1995007920-A1 NUCLEOTIDE ANALOGS GILEAD SCIENCES, INC. (US) 1995-03-23 — — WO disclosed
WO-1995007919-A1 METHOD FOR DOSING THERAPEUTIC COMPOUNDS GILEAD SCIENCES, INC. (US) 1995-03-23 — — WO disclosed
EP-0408371-B1 Hemoregulatory peptides SMITHKLINE BEECHAM CORP (US) 1994-09-28 — — EP disclosed
CN-1077960-A HEMOREGULATORY PEPTIDES SMITHKLINE BEECHAM CORP (US) 1993-11-03 — — CN disclosed
CN-1054773-A HEMOREGULATORY PEPTIDES SMITHKLINE BEECHAM CORP (US) 1991-09-25 — — CN disclosed
EP-0408371-A1 Hemoregulatory peptides SMITHKLINE BEECHAM CORPORATION (US) 1991-01-16 — — EP disclosed
JP-S6327499-A ALPHA,ALPHA'-DIAMINOSUBERIC ACID DERIVATIVE ASAHI CHEM IND CO LTD 1988-02-05 — — JP disclosed
US-3957760-A AMINO ACID DERIVATIVES E. R. SQUIBB & SONS, INC. (US) 1976-05-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220096669-A1 SILICON-FLUORIDE ACCEPTOR SUBSTITUTED RADIOPHARMACEUTICALS AND PRECURSORS THEREOF FOLH1, KLK3, FRS2 TSHR 347/4885LMNA 3950/4885NFKB1 4237/4885
US-10759748-B2 Compounds as L-cystine crystallization inhibitors and uses thereof ATP6V1B1, GLS, REN TSHR 2997/4885LMNA 549/4885NFKB1 2471/4885
US-12576169-B2 Silicon-fluoride acceptor substituted radiopharmaceuticals and precursors thereof KLK3, FOLH1, SLC7A1 TSHR 181/4885LMNA 1673/4885NFKB1 4388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.