Dehydrozingerone

Dehydrozingerone

SCHEMBL498224

COc1cc(C=CC(C)=O)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 3/20 1.00
CYP2D6 P10635 3/20 0.79
NFKB1 P19838 3/20 0.79
CYP1A2 P05177 2/20 0.79
ALOX5 P09917 2/20 0.79
HSD11B1 P28845 2/20 0.79
STAT3 P40763 2/20 0.79
NFKB2 Q00653 2/20 0.79
RELA Q04206 2/20 0.79
NFE2L2 Q16236 2/20 0.79
KDM4E B2RXH2 2/20 0.77
CA12 O43570 2/20 0.77
CA1 P00915 2/20 0.77
CA2 P00918 2/20 0.77
CA3 P07451 2/20 0.77
PKM P14618 2/20 0.77
CA4 P22748 2/20 0.77
CA6 P23280 2/20 0.77
CA5A P35218 2/20 0.77
SNCA P37840 2/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dehydrozingerone SCHEMBL30310276 1.00 APP (1.00) APPCYP2D6NFKB1CYP1A2ALOX5
Dehydrozingerone SCHEMBL498223 1.00 APP (1.00) APPCYP2D6NFKB1CYP1A2ALOX5
Dehydrozingerone SCHEMBL29691993 1.00 APP (1.00) APPCYP2D6NFKB1CYP1A2ALOX5
Dehydrozingerone SCHEMBL9104958 0.98 APP (0.97) APPCYP2D6NFKB1CYP1A2ALOX5
Dehydrozingerone SCHEMBL27764046 0.91 APP (0.83) APPCYP2D6NFKB1CYP1A2ALOX5
SCHEMBL29478095 0.88 CYP2D6 (1.00) APPCYP2D6NFKB1CYP1A2ALOX5
SCHEMBL1493283 0.88 CYP2D6 (1.00) APPCYP2D6NFKB1CYP1A2ALOX5
SCHEMBL1493282 0.88 CYP2D6 (1.00) APPCYP2D6NFKB1CYP1A2ALOX5
SCHEMBL30668505 0.88 CYP2D6 (1.00) APPCYP2D6NFKB1CYP1A2ALOX5
SCHEMBL9907021 0.88 APP (0.78) APPCYP2D6NFKB1CYP1A2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 769 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250327100-A1 Strain of Pseudomonas Putida Genetically Modified to Express a Benzalacetone Reductase BGENE GENETICS (FR) 2025-10-23 US claimed
US-20250171750-A1 Modified Polyketide Synthase Enzymes and Uses Thereof BGENE GENETICS (FR) 2025-05-29 US claimed
EP-4560015-A2 MODIFIED POLYKETIDE SYNTHASE ENZYMES AND USES THEREOF BGene Genetics (FR) 2025-05-28 EP claimed
US-20250033082-A1 METHOD AND COMPOSITION FOR REDUCING SOLVENT RELEASE FROM, AND REDUCING ODOR OF, AGROCHEMICAL FORMULATIONS ADAMA MAKHTESHIM LTD. (IL) 2025-01-30 US claimed
CN-115011576-B Aquilaria sinensis-derived III-type polyketide synthase AsPKS, and encoding gene and application thereof 中国医学科学院药用植物研究所 2024-10-25 CN claimed
CN-115161300-B Aquilaria sinensis-derived III-type polyketide synthase AsPKS, and encoding gene and application thereof 中国医学科学院药用植物研究所 2024-08-23 CN claimed
CN-114990084-B Aquilaria sinensis-derived III-type polyketide synthase AsPKS4, and encoding gene and application thereof 中国医学科学院药用植物研究所 2024-08-23 CN claimed
CN-118201991-A Methods and compositions for reducing solvent release from agrochemical formulations and reducing agrochemical formulation odor 安道麦马克西姆有限公司 2024-06-14 CN claimed
US-20240180852-A1 TREATMENT FOR MALIGNANT PLEURAL EFFUSION IN HUMANS SIGNPATH PHARMA, INC. 2024-06-06 US claimed
EP-4370674-A1 STRAIN OF PSEUDOMONAS PUTIDA GENETICALLY MODIFIED TO EXPRESS A BENZALACETONE REDUCTASE BGene Genetics (FR) 2024-05-22 EP claimed
US-6540997-B1 Shelf-stable, virulent preparation containing Agrobacterium cells, an acidulant and a phenolic compound SINNOTT ROBERT A (US) 2003-04-01 US claimed
EP-1292268-A2 AGENT FOR DYEING KERATIN CONTAINING FIBERS Henkel Kommanditgesellschaft auf Aktien (DE) 2003-03-19 EP claimed
WO-2001097764-A2 AGENT FOR DYEING KERATIN CONTAINING FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-27 WO claimed
US-6117223-A Hot melt inks containing polyketones XEROX CORPORATION (US) 2000-09-12 US claimed
EP-0873743-A2 Use of benzylidene-ketones for dyeing keratinous fibers Henkel Kommanditgesellschaft auf Aktien (DE) 1998-10-28 EP claimed
WO-1995018606-A9 CURCUMIN, ANALOGUES OF CURCUMIN AND NOVEL USES THEREOF 1997-05-22 WO claimed
EP-0738143-A1 CURCUMIN, ANALOGUES OF CURCUMIN AND NOVEL USES THEREOF RESEARCH DEVELOPMENT FOUNDATION (US) 1996-10-23 EP claimed
WO-1995018606-A1 CURCUMIN, ANALOGUES OF CURCUMIN AND NOVEL USES THEREOF RESEARCH DEVELOPMENT FOUNDATION (US) 1995-07-13 WO claimed
CN-1093079-A Adrenergic blocking agents for beta-type cells derived from compounds of the guaiacol class and their dehydrogenated compounds CHEN YINGJUN (CN) 1994-10-05 CN claimed
US-4927805-A Hydrolysis of curcumin MALLINCKRODT, INC. (US) 1990-05-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240180852-A1 TREATMENT FOR MALIGNANT PLEURAL EFFUSION IN HUMANS MTDH, PLEC, LPCAT3 APP 3737/4885CYP2D6 3138/4885NFKB1 793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.