Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.97 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.77 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.77 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.77 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.77 |
| ▸ | STAT3 | P40763 | 2/20 | 0.77 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.77 |
| ▸ | RELA | Q04206 | 2/20 | 0.77 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | CA12 | O43570 | 2/20 | 0.74 |
| ▸ | CA1 | P00915 | 2/20 | 0.74 |
| ▸ | CA2 | P00918 | 2/20 | 0.74 |
| ▸ | CA3 | P07451 | 2/20 | 0.74 |
| ▸ | PKM | P14618 | 2/20 | 0.74 |
| ▸ | CA4 | P22748 | 2/20 | 0.74 |
| ▸ | CA6 | P23280 | 2/20 | 0.74 |
| ▸ | CA5A | P35218 | 2/20 | 0.74 |
| ▸ | SNCA | P37840 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dehydrozingerone SCHEMBL30310276 | 0.98 | APP (1.00) | APPCYP2D6NFKB1CYP1A2ALOX5 | |
| Dehydrozingerone SCHEMBL498224 | 0.98 | APP (1.00) | APPCYP2D6NFKB1CYP1A2ALOX5 | |
| Dehydrozingerone SCHEMBL29691993 | 0.98 | APP (1.00) | APPCYP2D6NFKB1CYP1A2ALOX5 | |
| Dehydrozingerone SCHEMBL498223 | 0.98 | APP (1.00) | APPCYP2D6NFKB1CYP1A2ALOX5 | |
| Dehydrozingerone SCHEMBL27764046 | 0.90 | APP (0.83) | APPCYP2D6NFKB1CYP1A2ALOX5 | |
| SCHEMBL30668505 | 0.87 | CYP2D6 (1.00) | APPCYP2D6NFKB1CYP1A2ALOX5 | |
| SCHEMBL1493283 | 0.87 | CYP2D6 (1.00) | APPCYP2D6NFKB1CYP1A2ALOX5 | |
| SCHEMBL1493282 | 0.87 | CYP2D6 (1.00) | APPCYP2D6NFKB1CYP1A2ALOX5 | |
| SCHEMBL29478095 | 0.87 | CYP2D6 (1.00) | APPCYP2D6NFKB1CYP1A2ALOX5 | |
| SCHEMBL9907021 | 0.86 | APP (0.78) | APPCYP2D6NFKB1CYP1A2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649033-B1 | COMPOSITIONS AND METHODS FOR STABILIZING INGREDIENTS USING 2,4-PENTANEDIONE COMPOUNDS | SYTHEON LTD (US) | 2018-10-17 | — | — | EP | disclosed |
| US-8617528-B2 | Compositions and methods for stabilizing ingredients using 2,4-pentanedione compounds | SYTHEON LTD. (US) | 2013-12-31 | — | — | US | disclosed |
| US-20120141395-A1 | COMPOSITIONS AND METHODS FOR STABILIZING INGREDIENTS USING 2,4-PENTANEDIONE COMPOUNDS | SYTHEON LIMITED (US) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120141395-A1 | COMPOSITIONS AND METHODS FOR STABILIZING INGREDIENTS USING 2,4-PENTANEDIONE COMPOUNDS | HPD, GPX4, RBP4 | APP 448/4885CYP2D6 1065/4885NFKB1 2839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.