SCHEMBL4982707

SCHEMBL4982707

O=C(OC12C=CC(CC1)C2)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.38
LMNA P02545 3/20 0.38
F2 P00734 1/20 0.38
KMT2A Q03164 4/20 0.37
TSHR P16473 3/20 0.37
MEN1 O00255 2/20 0.37
ATM Q13315 1/20 0.37
CHRNA7 P36544 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
HTR3E A5X5Y0 1/20 0.35
HTR3B O95264 1/20 0.35
HTR3A P46098 1/20 0.35
HTR3D Q70Z44 1/20 0.35
HTR3C Q8WXA8 1/20 0.35
CYP1A2 P05177 2/20 0.35
CYP2D6 P10635 1/20 0.35
SCN1A P35498 1/20 0.35
SCN2A Q99250 1/20 0.35
SCN3A Q9NY46 1/20 0.35
EPHX2 P34913 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8034868 0.74 ALOX15 (0.36) KMT2AMEN1
SCHEMBL9825741 0.68 LMNA (0.43) GAALMNAF2KMT2ATSHR
SCHEMBL30526381 0.67 F2 (0.48) GAALMNAF2KMT2ATSHR
SCHEMBL5150629 0.67 LMNA (0.44) GAALMNAF2KMT2ATSHR
SCHEMBL29414430 0.67 TSHR (0.40) GAALMNAF2KMT2ATSHR
SCHEMBL1426503 0.66 GAA (0.49) GAALMNAF2KMT2ATSHR
SCHEMBL11480995 0.66 TSHR (0.41) GAALMNAF2KMT2ATSHR
SCHEMBL10896186 0.66 ALDH1A1 (0.42) GAALMNAF2KMT2ATSHR
SCHEMBL28882340 0.66 GAA (0.39) GAALMNAF2KMT2ATSHR
SCHEMBL16861396 0.65 TSHR (0.52) GAALMNAF2KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7365815-B2 Phase retardation film and liquid crystal display device including the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-04-29 US disclosed
US-20050280758-A1 Phase retardation film and liquid crystal display device including the same SUMITOMO CHEMICAL COMPANY, LIMITED 2005-12-22 US disclosed
EP-1607774-A1 Phase retardation film and liquid crystal display device including the same Sumitomo Chemical Company, Limited (JP) 2005-12-21 EP disclosed
US-20050185124-A1 Liquid crystal display SUMITOMO CHEMICAL COMPANY, LIMITED 2005-08-25 US disclosed