SCHEMBL4984737

SCHEMBL4984737

CC1(O)C[C@@H](O)[C@H](CO)O1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE4D Q08499 1/20 0.31
GBA1 P04062 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24025862 1.00 PDE4D (0.31) PDE4DGBA1
SCHEMBL6447297 1.00 PDE4D (0.31) PDE4DGBA1
SCHEMBL15424098 1.00 PDE4D (0.31) PDE4DGBA1
SCHEMBL4984741 1.00 PDE4D (0.31) PDE4DGBA1
SCHEMBL18797772 0.79 SYNJ2 (0.30) PDE4D
SCHEMBL4436037 0.77
SCHEMBL14985186 0.77 PDE4D (0.31) PDE4D
SCHEMBL21842390 0.77 PDE4D (0.31) PDE4D
SCHEMBL12899666 0.77 GAA (0.31) PDE4D
SCHEMBL4326330 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7361745-B2 Process for the preparation of 1-chloro-3,5-di-o-acyl-2-deoxy-l-ribofuranoside derivatives INALCO S.P.A. (IT) 2008-04-22 US claimed
US-20070083041-A1 Process for the preparation of 1-chloro-3,5-di-o-acyl-2-deoxy-l-ribofuranoside derivatives INALCO, S.P.A. (IT) 2007-04-12 US claimed
EP-1699805-A1 PROCESS FOR THE PREPARATION OF 1-CHLORO-3,5-DI-O-ACYL-2-DEOXY-L-RIBOFURANOSIDE DERIVATIVES Inalco S.p.A. (IT) 2006-09-13 EP claimed
WO-2005044832-A1 PROCESS FOR THE PREPARATION OF 1-CHLORO-3,5-DI-O-ACYL-2-DEOXY-L-RIBOFURANOSIDE DERIVATIVES INALCO S.P.A. (IT) 2005-05-19 WO claimed
EP-1699805-A1 PROCESS FOR THE PREPARATION OF 1-CHLORO-3,5-DI-O-ACYL-2-DEOXY-L-RIBOFURANOSIDE DERIVATIVES Inalco S.p.A. (IT) 2006-09-13 EP disclosed
WO-2005044832-A1 PROCESS FOR THE PREPARATION OF 1-CHLORO-3,5-DI-O-ACYL-2-DEOXY-L-RIBOFURANOSIDE DERIVATIVES INALCO S.P.A. (IT) 2005-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070083041-A1 Process for the preparation of 1-chloro-3,5-di-o-acyl-2-deoxy-l-ribofuranoside derivatives RNGTT, RNASEL, CPSF7 PDE4D 3071/4885GBA1 554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.