Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | FDPS | P14324 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21159060 | 0.87 | ALDH1A1 (0.58) | ALDH1A1TSHRFDPSMAPTCYP1A2 | |
| SCHEMBL5883213 | 0.83 | KDM4E (0.46) | ALDH1A1TSHRFDPSMAPTCYP1A2 | |
| SCHEMBL2432443 | 0.82 | ALDH1A1 (0.66) | ALDH1A1TSHRFDPSMAPTCYP1A2 | |
| SCHEMBL29957052 | 0.82 | ALDH1A1 (0.66) | ALDH1A1TSHRFDPSMAPTCYP1A2 | |
| SCHEMBL8584726 | 0.82 | ALOX5 (0.51) | ALDH1A1MAPTL3MBTL1ALOX5GABRA1 | |
| SCHEMBL8534293 | 0.82 | KDM4E (0.48) | ALDH1A1TSHRFDPSMAPTCYP1A2 | |
| SCHEMBL3303362 | 0.81 | CYP19A1 (0.56) | ALDH1A1TSHRFDPSCYP1A2AOX1 | |
| SCHEMBL9164276 | 0.80 | ALDH1A1 (0.64) | ALDH1A1TSHRFDPSMAPTCYP1A2 | |
| SCHEMBL30501077 | 0.80 | ALDH1A1 (0.64) | ALDH1A1TSHRFDPSMAPTCYP1A2 | |
| SCHEMBL24489075 | 0.79 | ALDH1A1 (0.61) | ALDH1A1TSHRFDPSMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151595-A1 | PYRROLO-BENZO-1,4-DIAZINES USEFUL AS SODIUM CHANNEL BLOCKERS | SCHERING CORPORATION (US) | 2010-12-29 | — | — | WO | disclosed |
| US-20080119518-A1 | 1-(Piperidin-4- Yl)-1H-Indole Derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
| US-20080119518-A1 | 1-(Piperidin-4- Yl)-1H-Indole Derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
| US-20080119518-A1 | 1-(Piperidin-4- Yl)-1H-Indole Derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
| EP-1847535-A1 | 1-(PIPERIDIN-4-YL)-1H-INDOLE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2007-10-24 | — | — | EP | disclosed |
| EP-1847535-A1 | 1-(PIPERIDIN-4-YL)-1H-INDOLE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2007-10-24 | — | — | EP | disclosed |
| US-5415854-A | Sunscreen agents | L'OREAL (FR) | 1995-05-16 | — | — | US | disclosed |
| US-5175340-A | Sunscreen agents, stabilizers | L'OREAL (FR) | 1992-12-29 | — | — | US | disclosed |
| EP-0392882-B1 | COSMETIC COMPOSITIONS CONTAINING DIORGANOPOLYSILOXANES WITH A BENZALMALONATE FUNCTION FOR SKIN AND HAIR PROTECTION, AND THEIR USE | L'OREAL (FR) | 1992-10-28 | — | — | EP | disclosed |
| EP-0358584-B1 | DIORGANOPOLYSILOXANES CONTAINING FUNCTIONAL BENZAL MALONATE GROUPS | RHONE-POULENC CHIMIE (FR) | 1992-09-16 | — | — | EP | disclosed |
| EP-0350386-B1 | UNSATURATED DERIVATIVES OF LIPID SOLUBLE BENZAL MALONATES, AND THEIR USE AS UV ABSORBERS IN THE COSMETIC FIELD | L'OREAL (FR) | 1992-04-08 | — | — | EP | disclosed |
| EP-0232143-B1 | META-BRIDGED STYRYLOXY RESINS | LOCTITE (IRELAND) Ltd. (IE) | 1991-10-09 | — | — | EP | disclosed |
| US-5053290-A | DIORGANOPOLYSILOXANES COMPRISING BENZALMALONATE FUNCTIONAL GROUPS | RHONE-POULENC CHIMIE (FR) | 1991-10-01 | — | — | US | disclosed |
| EP-0392882-A1 | Cosmetic compositions containing diorganopolysiloxanes with a benzalmalonate function for skin and hair protection, and their use | L'OREAL (FR) | 1990-10-17 | — | — | EP | disclosed |
| EP-0358584-A1 | Diorganopolysiloxanes containing functional benzal malonate groups | RHONE-POULENC CHIMIE (FR) | 1990-03-14 | — | — | EP | disclosed |
| EP-0350386-A1 | Unsaturated derivatives of lipid soluble benzal malonates, and their use as UV absorbers in the cosmetic field | L'OREAL (FR) | 1990-01-10 | — | — | EP | disclosed |
| EP-0232143-A2 | Meta-bridged styryloxy resins | LOCTITE (IRELAND) Ltd. (IE) | 1987-08-12 | — | — | EP | disclosed |
| US-4640849-A | Meta-bridged styryloxy resins | LOCTITE (IRELAND) LIMITED (IE) | 1987-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119518-A1 | 1-(Piperidin-4- Yl)-1H-Indole Derivatives | TPH1, HTR1D, HTR1B | ALDH1A1 91/4885TSHR 662/4885FDPS 4713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.