SCHEMBL4986477

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4991474	0.92	METAP1 (0.39)	METAP1ALDH1A1GABRPGABRDGABRA1
	SCHEMBL4987909	0.90	GABRP (0.38)	GABRPGABRDGABRA1GABRB1GABRG2
	SCHEMBL4986558	0.89	GPR84 (0.41)	ALDH1A1GABRPGABRDGABRA1GABRB1
	SCHEMBL4992240	0.87	SLC1A3 (0.37)	GABRPGABRDGABRA1GABRB1GABRG2
	SCHEMBL4987337	0.81	CACNA2D1 (0.44)	GABRPGABRDGABRA1GABRB1GABRG2
	SCHEMBL4994607	0.81	METAP1 (0.37)	METAP1ALDH1A1GABRPGABRDGABRA1
	SCHEMBL121853	0.81	ALDH1A1 (0.43)	METAP1ALDH1A1GABRPGABRDGABRA1
	SCHEMBL6061124	0.81	ALDH1A1 (0.43)	METAP1ALDH1A1GABRPGABRDGABRA1
	SCHEMBL1813910	0.81	ALDH1A1 (0.43)	METAP1ALDH1A1GABRPGABRDGABRA1
	SCHEMBL14892833	0.81	ALDH1A1 (0.43)	METAP1ALDH1A1GABRPGABRDGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.