SCHEMBL4986978

SCHEMBL4986978

CCOc1ccc(CC(=O)OC)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.58
CYP4A11 Q02928 1/20 0.58
ALDH1A1 P00352 4/20 0.57
NPC1 O15118 3/20 0.57
RAB9A P51151 3/20 0.57
HTT P42858 1/20 0.55
SMN1; SMN2 Q16637 4/20 0.54
HPGD P15428 2/20 0.54
MAPT P10636 1/20 0.52
POLB P06746 2/20 0.52
NQO1 P15559 1/20 0.52
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
CYP1A2 P05177 2/20 0.51
PLK1 P53350 1/20 0.51
LMNA P02545 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
CNR2 P34972 1/20 0.51
NLRP3 Q96P20 1/20 0.51
PARP10 Q53GL7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL458087 0.92 ACACB (0.59)
SCHEMBL2628190 0.86 SMN1; SMN2 (0.59) CYP4F2CYP4A11ALDH1A1NPC1RAB9A
SCHEMBL3333378 0.86 KDM4E (0.69) CYP4F2CYP4A11ALDH1A1NPC1RAB9A
SCHEMBL25255900 0.85 CYP4F2 (0.62) CYP4F2CYP4A11ALDH1A1NPC1RAB9A
SCHEMBL4275929 0.85 SMN1; SMN2 (0.58) CYP4F2CYP4A11ALDH1A1NPC1RAB9A
SCHEMBL12688088 0.85 NPC1 (0.70) CYP4F2CYP4A11ALDH1A1NPC1RAB9A
SCHEMBL181473 0.85 HPGD (0.61) ALDH1A1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL5551453 0.85 GAA (0.59) CYP4F2CYP4A11ALDH1A1NPC1RAB9A
SCHEMBL9584950 0.85 AKR1C3 (0.54) CYP4F2CYP4A11ALDH1A1NPC1RAB9A
SCHEMBL4113212 0.84 CYP4F2 (0.76) CYP4F2CYP4A11ALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109096420-B Catalyst for olefin polymerization and olefin polymerization method 中国石油化工股份有限公司 2021-05-11 CN claimed
US-RE49934-E1 Inhibitors of cellular metabolic processes SERVIER PHARMACEUTICALS LLC (US) 2024-04-23 US disclosed
CN-116554050-A Amide phenol derivative and application thereof 四川大学 2023-08-08 CN disclosed
CN-109890822-B Inhibitors of cellular metabolic processes 安吉奥斯医药品有限公司 2022-08-30 CN disclosed
US-11325914-B1 Inhibitors of cellular metabolic processes SERVIER PHARMACEUTICALS LLC (US) 2022-05-10 US disclosed
CN-109096420-B Catalyst for olefin polymerization and olefin polymerization method 中国石油化工股份有限公司 2021-05-11 CN disclosed
US-10800782-B2 Inhibitors of cellular metabolic processes Agios Pharmaceutical, Inc. (US) 2020-10-13 US disclosed
EP-3397616-B1 LSD1 INHIBITORS MIRATI THERAPEUTICS INC (US) 2020-06-10 EP disclosed
US-20190233424-A1 INHIBITORS OF CELLULAR METABOLIC PROCESSES SERVIER PHARMACEUTICALS LLC 2019-08-01 US disclosed
EP-3507290-A1 INHIBITORS OF CELLULAR METABOLIC PROCESSES Agios Pharmaceuticals, Inc. (US) 2019-07-10 EP disclosed
US-7384955-B2 Azaindole derivatives, preparations thereof, uses thereof and compositions containing them ASTRAZENECA AB (SE) 2008-06-10 US disclosed
US-7384955-B2 Azaindole derivatives, preparations thereof, uses thereof and compositions containing them ASTRAZENECA AB (SE) 2008-06-10 US disclosed
US-20070027179-A1 Azaindole derivatives, preparations thereof, uses thereof and compositions containing them ASTRAZENECA AB (SE) 2007-02-01 US disclosed
US-20070027179-A1 Azaindole derivatives, preparations thereof, uses thereof and compositions containing them ASTRAZENECA AB (SE) 2007-02-01 US disclosed
US-20070027179-A1 Azaindole derivatives, preparations thereof, uses thereof and compositions containing them ASTRAZENECA AB (SE) 2007-02-01 US disclosed
EP-1615922-A1 AZAINDOLE DERIVATIVES, PREPARATIONS THEREOF, USES THEREOF AND COMPOSITIONS CONTAINING THEM AstraZeneca AB (SE) 2006-01-18 EP disclosed
CN-1183107-C Alkynyl containing hydroxamic acid compounds as TACE inhibitors ���Ͽع����޹�˾ 2005-01-05 CN disclosed
WO-2004087704-A1 AZAINDOLE DERIVATIVES, PREPARATIONS THEREOF, USES THEREOF AND COMPOSITIONS CONTAINING THEM ASTRAZENECA AB (SE) 2004-10-14 WO disclosed
CN-1337945-A Alkynyl containing hydroxamic acid compounds as TACE inhibitors AMERICAN CYANAMID CO (US) 2002-02-27 CN disclosed
US-4560447-A Electrolytic process for preparation of α-alkylated acetic acid derivatives OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1985-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190233424-A1 INHIBITORS OF CELLULAR METABOLIC PROCESSES MNAT1, MAT2A, PCK2 CYP4F2 867/4885CYP4A11 2866/4885ALDH1A1 352/4885
US-10800782-B2 Inhibitors of cellular metabolic processes MNAT1, MAT2A, PCK2 CYP4F2 867/4885CYP4A11 2866/4885ALDH1A1 352/4885
US-20070027179-A1 Azaindole derivatives, preparations thereof, uses thereof and compositions containing them ADRA2A, ADRA1A, ADORA2A CYP4F2 1055/4885CYP4A11 660/4885ALDH1A1 404/4885
US-11325914-B1 Inhibitors of cellular metabolic processes MNAT1, MAT2A, PCK2 CYP4F2 867/4885CYP4A11 2866/4885ALDH1A1 352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.