Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.39 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4984385 | 0.91 | RIPK1 (0.39) | ALDH1A1TSHRPIK3CDPIK3R2PIK3CA | |
| SCHEMBL5781022 | 0.88 | HPGD (0.38) | ALDH1A1TSHRPIK3CDPIK3R2PIK3CA | |
| SCHEMBL5785036 | 0.88 | PIK3CD (0.42) | ALDH1A1TSHRPIK3CDPIK3R2PIK3CA | |
| SCHEMBL5785686 | 0.88 | HPGD (0.38) | ALDH1A1TSHRPIK3CDPIK3R2PIK3CA | |
| SCHEMBL4982158 | 0.87 | HPGD (0.39) | ALDH1A1TSHRPIK3CDPIK3R2PIK3CA | |
| SCHEMBL5783378 | 0.87 | LRRK2 (0.37) | ALDH1A1TSHRPIK3CDPIK3R2PIK3CA | |
| SCHEMBL4988846 | 0.86 | ALDH1A1 (0.39) | ALDH1A1TSHRPIK3CDPIK3R2PIK3CA | |
| SCHEMBL4987425 | 0.85 | HPGD (0.36) | ALDH1A1TSHRPIK3CDPIK3R2PIK3CA | |
| SCHEMBL4984335 | 0.85 | NNMT (0.44) | ALDH1A1TSHRPIK3CDPIK3R2PIK3CA | |
| SCHEMBL4982219 | 0.85 | HPGD (0.36) | ALDH1A1TSHRPIK3CDPIK3R2PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080125409-A1 | 1,5-Diheterocycle-1H-Triazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-05-29 | — | — | US | disclosed |
| US-20080125409-A1 | 1,5-Diheterocycle-1H-Triazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-05-29 | — | — | US | disclosed |
| EP-1803719-A1 | 1,5-DIHETEROCYCLE-1H-TRIAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080125409-A1 | 1,5-Diheterocycle-1H-Triazole Derivative | PTGS1, PTGER1, TBXA2R | ALDH1A1 185/4885TSHR 2787/4885PIK3CD 3266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.