Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | F7 | P08709 | 2/20 | 0.33 |
| ▸ | F3 | P13726 | 2/20 | 0.33 |
| ▸ | TDO2 | P48775 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5821413 | 0.86 | TDO2 (0.42) | KMT2AKDM4EMEN1ALDH1A1ELANE | |
| SCHEMBL3533214 | 0.76 | KDM4E (0.57) | KMT2AKDM4EMEN1ALDH1A1ELANE | |
| SCHEMBL30200573 | 0.73 | L3MBTL1 (0.44) | KMT2AKDM4EMEN1ALDH1A1ELANE | |
| SCHEMBL4163580 | 0.73 | L3MBTL1 (0.44) | KMT2AKDM4EMEN1ALDH1A1ELANE | |
| SCHEMBL7600946 | 0.73 | ELANE (0.54) | KMT2AKDM4EMEN1ALDH1A1ELANE | |
| SCHEMBL1964870 | 0.71 | ELANE (0.61) | KMT2AKDM4EMEN1ALDH1A1ELANE | |
| SCHEMBL19706880 | 0.71 | ALDH1A1 (0.50) | KDM4EALDH1A1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL11884986 | 0.71 | ACHE (0.37) | KDM4EALDH1A1TDO2HTTIDO1 | |
| SCHEMBL11121163 | 0.71 | ALDH2 (0.42) | KMT2AKDM4EMEN1ALDH1A1ELANE | |
| SCHEMBL30398598 | 0.69 | L3MBTL1 (0.41) | KMT2AKDM4EMEN1ALDH1A1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954283-A2 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | Hydra Biosciences, Inc. (US) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007056124-A2 | COMPOUNDS FOR MODULATING TRPV3 FUNCTION | HYDRA BIOSCIENCES, INC. (US) | 2007-05-18 | — | — | WO | disclosed |