Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4986014 | 0.73 | KDM4E (0.33) | KDM4EHPGDTSHR | |
| SCHEMBL4986017 | 0.72 | KDM4E (0.39) | KDM4EHPGDTSHR | |
| SCHEMBL10151268 | 0.61 | SSTR5 (0.33) | — | |
| SCHEMBL4988081 | 0.61 | TSHR (0.37) | TSHR | |
| SCHEMBL10124614 | 0.61 | — | — | |
| SCHEMBL10151278 | 0.61 | — | — | |
| SCHEMBL10124603 | 0.59 | — | — | |
| SCHEMBL10151271 | 0.59 | — | — | |
| SCHEMBL542452 | 0.58 | LMNA (0.36) | KDM4ETSHR | |
| SCHEMBL5062854 | 0.56 | LMNA (0.34) | KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7361755-B2 | Transition-metal-catalyzed process for the conversion of alkenes to sterically hindered substituted n-alkoxyamines | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-04-22 | — | — | US | claimed |
| US-20050085636-A1 | Transition-metal-catalyzed process for the conversion of alkenes to sterically hindered substituted n-alkoxyamines | CIBA SPECIALTY CHEMICALS CORP. | 2005-04-21 | — | — | US | claimed |
| EP-1456173-A1 | TRANSITION-METAL-CATALYZED PROCESS FOR THE CONVERSION OF ALKENES TO STERICALLY HINDERED SUBSTITUTED N-ALKOXYAMINES | Ciba SC Holding AG (CH) | 2004-09-15 | — | — | EP | claimed |
| WO-2003053931-A1 | TRANSITION-METAL-CATALYZED PROCESS FOR THE CONVERSION OF ALKENES TO STERICALLY HINDERED SUBSTITUTED N-ALKOXYAMINES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-07-03 | — | — | WO | claimed |
| US-7361755-B2 | Transition-metal-catalyzed process for the conversion of alkenes to sterically hindered substituted n-alkoxyamines | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-04-22 | — | — | US | disclosed |
| US-7361755-B2 | Transition-metal-catalyzed process for the conversion of alkenes to sterically hindered substituted n-alkoxyamines | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-04-22 | — | — | US | disclosed |
| US-7361755-B2 | Transition-metal-catalyzed process for the conversion of alkenes to sterically hindered substituted n-alkoxyamines | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-04-22 | — | — | US | disclosed |
| US-20050085636-A1 | Transition-metal-catalyzed process for the conversion of alkenes to sterically hindered substituted n-alkoxyamines | CIBA SPECIALTY CHEMICALS CORP. | 2005-04-21 | — | — | US | disclosed |
| EP-1456173-A1 | TRANSITION-METAL-CATALYZED PROCESS FOR THE CONVERSION OF ALKENES TO STERICALLY HINDERED SUBSTITUTED N-ALKOXYAMINES | Ciba SC Holding AG (CH) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003053931-A1 | TRANSITION-METAL-CATALYZED PROCESS FOR THE CONVERSION OF ALKENES TO STERICALLY HINDERED SUBSTITUTED N-ALKOXYAMINES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050085636-A1 | Transition-metal-catalyzed process for the conversion of alkenes to sterically hindered substituted n-alkoxyamines | PNMT, NNMT, TET2 | NPC1 1964/4885RAB9A 2098/4885KDM4E 1018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.