SCHEMBL4986017

SCHEMBL4986017

CCC1(C)NC(=O)C(C)(CC)N1O

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
HPGD P15428 1/20 0.39
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
TSHR P16473 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4986014 0.78 KDM4E (0.33) KDM4EHPGDALDH1A1POLBGAA
SCHEMBL4988086 0.72 NPC1 (0.33) KDM4EHPGDTSHR
SCHEMBL4954519 0.63 TSHR (0.34) KDM4EHPGDTSHRNPSR1LMNA
SCHEMBL1138530 0.63 POLB (0.33) KDM4EHPGDPOLB
SCHEMBL4952323 0.61 LMNA (0.32) KDM4EHPGDLMNA
SCHEMBL9190795 0.61 TSHR (0.32) KDM4ETSHRNPSR1LMNA
SCHEMBL542452 0.61 LMNA (0.36) KDM4ETSHRNPSR1LMNA
SCHEMBL6258811 0.60 ALDH1A1 (0.31) ALDH1A1
SCHEMBL632188 0.60 LMNA (0.34) KDM4ETSHRNPSR1LMNA
SCHEMBL5062854 0.60 LMNA (0.34) KDM4ETSHRNPSR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120313570-A1 NONAQUEOUS ELECTROLYTE AND NONAQUEOUS ELECTROLYTE BATTERY, AND BATTERY PACK, ELECTRONIC APPLIANCE, ELECTRIC VEHICLE, ELECTRICITY STORAGE APPARATUS, AND ELECTRIC POWER SYSTEM EACH USING NONAQUEOUS ELECTROLYTE BATTERY SONY CORPORATION (JP) 2012-12-13 US disclosed
US-20120313570-A1 NONAQUEOUS ELECTROLYTE AND NONAQUEOUS ELECTROLYTE BATTERY, AND BATTERY PACK, ELECTRONIC APPLIANCE, ELECTRIC VEHICLE, ELECTRICITY STORAGE APPARATUS, AND ELECTRIC POWER SYSTEM EACH USING NONAQUEOUS ELECTROLYTE BATTERY SONY CORPORATION (JP) 2012-12-13 US disclosed
US-7361755-B2 Transition-metal-catalyzed process for the conversion of alkenes to sterically hindered substituted n-alkoxyamines CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-04-22 US disclosed
US-20050085636-A1 Transition-metal-catalyzed process for the conversion of alkenes to sterically hindered substituted n-alkoxyamines CIBA SPECIALTY CHEMICALS CORP. 2005-04-21 US disclosed
EP-1178010-B1 Colorless aqueous ammonium sulfide solution DU PONT (US) 2005-03-30 EP disclosed
EP-1456173-A1 TRANSITION-METAL-CATALYZED PROCESS FOR THE CONVERSION OF ALKENES TO STERICALLY HINDERED SUBSTITUTED N-ALKOXYAMINES Ciba SC Holding AG (CH) 2004-09-15 EP disclosed
US-6664353-B2 Compounds providing stable free radical-mediated polymerization processes which yield polymers having low polydispersity at enhanced rates of polymerization and enhanced monomer to polymer conversions CIBA SPECIALTY CHEMICALS CORPORATION 2003-12-16 US disclosed
US-20030149208-A1 Method of controlling polymer molecular weight and structure ANDERSON ALBERT G (US) 2003-08-07 US disclosed
US-20030125494-A1 Heterocyclic alkoxyamines as regulators in controlled radical polymerization processes NESVADBA PETER (CH) 2003-07-03 US disclosed
WO-2003053931-A1 TRANSITION-METAL-CATALYZED PROCESS FOR THE CONVERSION OF ALKENES TO STERICALLY HINDERED SUBSTITUTED N-ALKOXYAMINES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-07-03 WO disclosed
EP-0951485-B1 METHOD OF CONTROLLING POLYMER MOLECULAR WEIGHT AND STRUCTURE DU PONT (US) 2003-04-02 EP disclosed
US-6479608-B1 Heterocyclic alkoxyamines as regulators in controlled radical polymerization processes CIBA SPECIALTY CHEMICALS CORPORATION 2002-11-12 US disclosed
US-20020058772-A1 Method of controlling polymer molecular weight and structure E. I. DU PONT DE NEMOURS AND COMPANY 2002-05-16 US disclosed
US-6388004-B1 AQUEOUS SOLUTION OF AMMONIUM SULFIDE CONTAINING SODIUM THIOCYANATE E.I. DU PONT DE NEMOURS AND COMPANY 2002-05-14 US disclosed
EP-1178010-A1 Colorless aqueous ammonium sulfide solution E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-02-06 EP disclosed
US-6271340-B1 LIVING FREE RADICAL POLYMERIZATION INITIATED BY AN ALKOXYAMINE INITIATOR OR NITROXIDE E. I. DU PONT DE NEMOURS AND COMPANY 2001-08-07 US disclosed
EP-0951485-A2 METHOD OF CONTROLLING POLYMER MOLECULAR WEIGHT AND STRUCTURE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-10-27 EP disclosed
WO-1998030601-A2 METHOD OF CONTROLLING POLYMER MOLECULAR WEIGHT AND STRUCTURE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-07-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030149208-A1 Method of controlling polymer molecular weight and structure NOS2, NOS1, NOS3 KDM4E 356/4885HPGD 246/4885ALDH1A1 2071/4885
US-20050085636-A1 Transition-metal-catalyzed process for the conversion of alkenes to sterically hindered substituted n-alkoxyamines PNMT, NNMT, TET2 KDM4E 1018/4885HPGD 2393/4885ALDH1A1 859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.