Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4984310 | 0.80 | TRPV1 (0.65) | TRPV1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL5128348 | 0.79 | TRPV1 (0.68) | TRPV1HDAC3HDAC11HDAC8HDAC6 | |
| SCHEMBL4988297 | 0.78 | TRPV1 (0.88) | TRPV1RAB9ANPC1HDAC3HDAC11 | |
| SCHEMBL4986940 | 0.78 | TRPV1 (0.62) | TRPV1RAB9ANPC1HDAC3HDAC8 | |
| SCHEMBL4900109 | 0.78 | TRPV1 (0.56) | TRPV1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL24445076 | 0.78 | HDAC4 (0.48) | RAB9ANPC1KMT2ACHRNA7SMN1; SMN2 | |
| SCHEMBL24444427 | 0.78 | HDAC4 (0.48) | RAB9ANPC1KMT2ACHRNA7SMN1; SMN2 | |
| SCHEMBL4987540 | 0.77 | TRPV1 (0.71) | TRPV1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL16022191 | 0.76 | HDAC8 (0.76) | RAB9ANPC1HDAC3HDAC11HDAC8 | |
| SCHEMBL5781167 | 0.76 | TRPV1 (0.72) | TRPV1RAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108676-A1 | Benzothiazolecarboxamides | NEW BENZOTHIAZOLECARBOXAMIDES (SE) | 2008-05-08 | — | — | US | claimed |
| US-20080108676-A1 | Benzothiazolecarboxamides | NEW BENZOTHIAZOLECARBOXAMIDES (SE) | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108676-A1 | Benzothiazolecarboxamides | QDPR, NDUFB5, NDUFB6 | TRPV1 356/4885RAB9A 3886/4885NPC1 1580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.