Sugi Predict

Sugi Predict / Compounds / SCHEMBL4989

SCHEMBL4989

SCHEMBL4989

O=C(O)c1cccc(Br)n1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 6/20 0.70
▸ ALOX15 P16050 1/20 0.70
▸ TSHR P16473 1/20 0.70
▸ ACMSD Q8TDX5 1/20 0.70
▸ TDP1 Q9NUW8 1/20 0.70
▸ ALDH1A1 P00352 3/20 0.54
▸ HPGD P15428 1/20 0.54
▸ GRM5 P41594 1/20 0.49
▸ LMNA P02545 3/20 0.48
▸ GNE Q9Y223 1/20 0.47
▸ KMT2A Q03164 2/20 0.46
▸ MGAM O43451 1/20 0.45
▸ NAPRT Q6XQN6 1/20 0.45
▸ P4HTM Q9NXG6 1/20 0.45
▸ L3MBTL1 Q9Y468 1/20 0.45
▸ ECE1 P42892 1/20 0.43
▸ CTSA P10619 1/20 0.42
▸ MEN1 O00255 1/20 0.41
▸ CA1 P00915 1/20 0.41
▸ CA2 P00918 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29940784 1.00 KDM4E (0.70) KDM4EALOX15TSHRACMSDTDP1
Hydrochloric Acid SCHEMBL4538345 0.98 KDM4E (0.67) KDM4EALOX15TSHRACMSDTDP1
Acetic Acid SCHEMBL28860398 0.94 KDM4E (0.61) KDM4EALOX15TSHRACMSDTDP1
Acetamide SCHEMBL28213479 0.90 KDM4E (0.57) KDM4EALOX15TSHRACMSDTDP1
SCHEMBL28905979 0.89 KDM4E (0.55) KDM4EALOX15TSHRACMSDTDP1
SCHEMBL17258354 0.88 KDM4E (0.59) KDM4EALOX15TSHRACMSDTDP1
SCHEMBL960010 0.84 ALDH1A1 (0.51) KDM4EALOX15TSHRACMSDTDP1
Dipicolinic Acid SCHEMBL720696 0.83 KDM4E (1.00) KDM4EALOX15TSHRACMSDTDP1
Dipicolinic Acid SCHEMBL34595 0.83 KDM4E (1.00) KDM4EALOX15TSHRACMSDTDP1
SCHEMBL13932169 0.82 KDM4E (0.50) KDM4EALOX15TSHRACMSDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1517 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010834-A Piroctone derivative, and preparation method and application thereof 中国海洋大学 2026-05-12 — — CN claimed
EP-3845528-B1 PYRAZOLE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF AND USE THEREOF AS IRAK4 INHIBITORS ARTIVILA SHENZHEN INNOVATION CENTER LTD (CN) 2023-10-11 — — EP claimed
CN-115417814-A Synthetic method of 2-bromo-6-cyanopyridine 安徽大学 2022-12-02 — — CN claimed
CN-115246787-A Meta-disubstituted compound, preparation thereof and application thereof in preventing and treating mosquito and plant pathogenic bacteria 吉林省达凯生物医药有限公司 2022-10-28 — — CN claimed
CN-111440174-B Pyridine amide compound and preparation method and application thereof 广州医科大学 2021-07-09 — — CN claimed
CN-111440174-A Pyridine amide compound and preparation method and application thereof 广州医科大学 2020-07-24 — — CN claimed
CN-106732381-B A kind of PM2.5 adsorbent and preparation method thereof 华北电力大学（保定） 2019-04-30 — — CN claimed
CN-109593085-A Pyridine-amide-oxazoline ligand, its synthetic method and its metal complex and purposes 温州大学 2019-04-09 — — CN claimed
CN-108148062-A A kind of preparation method and applications of 2- (pyridine bromide base) benzo double imidazole compound 中国科学院大连化学物理研究所 2018-06-12 — — CN claimed
CN-106732381-A A kind of PM2.5 adsorbents and preparation method thereof 华北电力大学（保定） 2017-05-31 — — CN claimed
EP-2167077-A2 ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR Bayer Schering Pharma Aktiengesellschaft (DE) 2010-03-31 — — EP claimed
CN-101641342-A Thiazolidine derivatives ACTELION PHARMACEUTICAL LTD CH 2010-02-03 — — CN claimed
EP-2125760-A2 THIAZOLIDINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS Actelion Pharmaceuticals Ltd. (CH) 2009-12-02 — — EP claimed
CN-101563328-A Substituted heteroaryl pyridopyrimidinone derivatives SANOFI AVENTIS (FR) 2009-10-21 — — CN claimed
US-20090069320-A1 Substituted 4-Amino-Quinazoline Compounds with Metabotropic Glutamate Receptor Regulating Activity and Uses Thereof GRUENENTHAL GMBH (DE) 2009-03-12 — — US claimed
US-20090023741-A1 ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR BAYER SCHERING PHARMA AG (DE) 2009-01-22 — — US claimed
CN-101343366-A Nano-laminal compound with regular array of pyridine and its derivant, and preparation thereof UNIV SHANGHAI (CN) 2009-01-14 — — CN claimed
WO-2008152099-A2 ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-12-18 — — WO claimed
WO-2008117241-A2 THIAZOLIDINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS ACTELION PHARMACEUTICALS LTD (CH) 2008-10-02 — — WO claimed
US-20070049618-A1 Isoindole-imide compounds and compositions comprising and methods of using the same CELGENE CORPORATION 2007-03-01 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090023741-A1 ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR PTGER2, PTGER1, PTGDR2 KDM4E 3048/4885ALOX15 32/4885TSHR 498/4885
US-20070049618-A1 Isoindole-imide compounds and compositions comprising and methods of using the same SI, CYP3A5, CYP2D6 KDM4E 1501/4885ALOX15 3231/4885TSHR 3814/4885
US-20090069320-A1 Substituted 4-Amino-Quinazoline Compounds with Metabotropic Glutamate Receptor Regulating Activity and Uses Thereof GRM1, GRIN1, GRM2 KDM4E 2026/4885ALOX15 3815/4885TSHR 991/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.