Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CTSA | P10619 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13932169 | 0.98 | KDM4E (0.50) | ALDH1A1HPGDGRM5KDM4EALOX15 | |
| SCHEMBL9828649 | 0.86 | KMT2A (0.53) | ALDH1A1HPGDGRM5KDM4EALOX15 | |
| SCHEMBL4989 | 0.84 | KDM4E (0.70) | ALDH1A1HPGDGRM5KDM4EALOX15 | |
| SCHEMBL29940784 | 0.84 | KDM4E (0.70) | ALDH1A1HPGDGRM5KDM4EALOX15 | |
| SCHEMBL24141717 | 0.82 | KDM4E (0.44) | ALDH1A1HPGDGRM5KDM4EALOX15 | |
| SCHEMBL2825924 | 0.82 | ALDH1A1 (0.49) | ALDH1A1HPGDGRM5KDM4EALOX15 | |
| SCHEMBL40454 | 0.82 | GRM5 (0.51) | ALDH1A1HPGDGRM5KDM4EALOX15 | |
| SCHEMBL6744 | 0.82 | GRM5 (0.51) | ALDH1A1HPGDGRM5KDM4EALOX15 | |
| SCHEMBL30041316 | 0.82 | GRM5 (0.51) | ALDH1A1HPGDGRM5KDM4EALOX15 | |
| SCHEMBL25307554 | 0.82 | ALDH1A1 (0.49) | ALDH1A1HPGDGRM5KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240260448-A1 | Metal Complexes | UDC IRELAND LIMITED (IE) | 2024-08-01 | — | — | US | disclosed |
| US-11917901-B2 | Metal complexes | UDC IRELAND LIMITED (IE) | 2024-02-27 | — | — | US | disclosed |
| US-11393988-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2022-07-19 | — | — | US | disclosed |
| US-11005050-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-05-11 | — | — | US | disclosed |
| EP-3424936-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2021-04-07 | — | — | EP | disclosed |
| CN-105916868-B | Metal complexes | 默克专利有限公司 | 2020-06-23 | — | — | CN | disclosed |
| EP-3424936-A1 | METAL COMPLEXES | Merck Patent GmbH (DE) | 2019-01-09 | — | — | EP | disclosed |
| EP-3102650-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2018-08-29 | — | — | EP | disclosed |
| EP-2882763-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2018-08-22 | — | — | EP | disclosed |
| US-20180090694-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2018-03-29 | — | — | US | disclosed |
| EP-2254896-A1 | METAL COMPLEXES | Merck Patent GmbH (DE) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009118087-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2009-10-01 | — | — | WO | disclosed |
| US-20070082284-A1 | Metal complexes with bipodal ligands | MERCK PATENT GMBH (DE) | 2007-04-12 | — | — | US | disclosed |
| US-20070082284-A1 | Metal complexes with bipodal ligands | MERCK PATENT GMBH (DE) | 2007-04-12 | — | — | US | disclosed |
| US-20070082284-A1 | Metal complexes with bipodal ligands | MERCK PATENT GMBH (DE) | 2007-04-12 | — | — | US | disclosed |
| CN-1894269-A | Metal complexes with bipodal ligands | MERCK PATENT GMBH (DE) | 2007-01-10 | — | — | CN | disclosed |
| EP-1678190-A1 | METAL COMPLEXES WITH BIPODAL LIGANDS | Merck Patent GmbH (DE) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042550-A1 | METAL COMPLEXES WITH BIPODAL LIGANDS | MERCK PATENT GMBH (DE) | 2005-05-12 | — | — | WO | disclosed |
| US-5861140-A | Tripodal paramagnetic contrast agents for MR imaging | HOECHST CELANESE CORP. (US) | 1999-01-19 | — | — | US | disclosed |
| US-5861138-A | Ligands for MRI contrast agent | HOECHST CELANESE CORP. (US) | 1999-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11393988-B2 | Metal complexes | SOD1, AP1M1, AP3M1 | ALDH1A1 3721/4885HPGD 3882/4885GRM5 1139/4885 |
| US-11005050-B2 | Metal complexes | SOD1, AP1M1, AP3M1 | ALDH1A1 3721/4885HPGD 3882/4885GRM5 1139/4885 |
| US-20180090694-A1 | METAL COMPLEXES | AP3M1, AP2M1, AP1M1 | ALDH1A1 2839/4885HPGD 4287/4885GRM5 2135/4885 |
| US-11917901-B2 | Metal complexes | MCOLN2, MCOLN1, AP1M1 | ALDH1A1 1631/4885HPGD 3283/4885GRM5 1939/4885 |
| US-20240260448-A1 | Metal Complexes | SOD1, AP1M1, AP3M1 | ALDH1A1 3721/4885HPGD 3882/4885GRM5 1139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.