Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | BLM | P54132 | 1/20 | 0.66 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.66 |
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | KIF11 | P52732 | 4/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.47 |
| ▸ | GRM8 | O00222 | 1/20 | 0.47 |
| ▸ | GRM6 | O15303 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GSR | P00390 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutamine SCHEMBL8630970 | 0.98 | KMT2A (0.63) | KMT2AALOX15BLMPMP22LTA4H | |
| D-Glutamate SCHEMBL561574 | 0.88 | SLC1A3 (0.64) | KMT2AALOX15BLMPMP22LTA4H | |
| Biphenyl SCHEMBL8982408 | 0.86 | KMT2A (0.70) | KMT2AALOX15BLMPMP22LTA4H | |
| Biphenyl SCHEMBL8982412 | 0.86 | KMT2A (0.70) | KMT2AALOX15BLMPMP22LTA4H | |
| Glutamine SCHEMBL28281766 | 0.85 | ALOX15 (0.91) | KMT2AALOX15BLMPMP22LTA4H | |
| SCHEMBL8618296 | 0.85 | KMT2A (0.48) | KMT2AALOX15BLMPMP22LTA4H | |
| Homoserine SCHEMBL6051437 | 0.84 | KIF11 (0.49) | KMT2AALOX15BLMPMP22LTA4H | |
| Glutamine SCHEMBL15269081 | 0.84 | KMT2A (0.68) | KMT2AALOX15BLMPMP22LTA4H | |
| Glutamine SCHEMBL15269077 | 0.84 | KMT2A (0.68) | KMT2AALOX15BLMPMP22LTA4H | |
| Glutamine SCHEMBL7902170 | 0.83 | ALOX15 (0.66) | KMT2AALOX15BLMPMP22LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240065990-A1 | METHODS, COMPOUNDS, COMPOSITIONS AND VEHICLES FOR DELIVERING 3-AMINO-1-PROPANESULFONIC ACID | BELLUS HEALTH INC (CA) | 2024-02-29 | — | — | US | claimed |
| EP-3851447-B1 | METHODS, COMPOUNDS, COMPOSITIONS AND VEHICLES FOR DELIVERING 3-AMINO-1-PROPANESULFONIC ACID | BELLUS HEALTH INC (CA) | 2023-09-06 | — | — | EP | claimed |
| EP-3851447-A1 | METHODS, COMPOUNDS, COMPOSITIONS AND VEHICLES FOR DELIVERING 3-AMINO-1-PROPANESULFONIC ACID | BHI Limited Partnership (CA) | 2021-07-21 | — | — | EP | claimed |
| US-20080146642-A1 | Propanesulfonic acid amino acid prodrugs that can deliver 3-amino-1-propanesulfonic acid (3APS) by minimizing metabolism associated with that drug, particularly compounds that block or protect amino group of 3APS such that it avoids metabolism by transaminases or monoamine oxidase; Alzheimer's disease | BELLUS HEALTH INC. (CA) | 2008-06-19 | — | — | US | claimed |
| CN-119751538-A | Medicine for removing fat or fat pad and application | 西安莱格瑞生物科技有限公司 | 2025-04-04 | — | — | CN | disclosed |
| CN-117815245-A | Medicine for removing fat or fat pad and application | 西安莱格瑞生物科技有限公司 | 2024-04-05 | — | — | CN | disclosed |
| US-20240065990-A1 | METHODS, COMPOUNDS, COMPOSITIONS AND VEHICLES FOR DELIVERING 3-AMINO-1-PROPANESULFONIC ACID | BELLUS HEALTH INC (CA) | 2024-02-29 | — | — | US | disclosed |
| EP-4289820-A2 | COMPOUNDS FOR USE IN TREATING ALZHEIMER'S DISEASE IN APOE4+/+ PATIENTS | Alzheon, Inc. (US) | 2023-12-13 | — | — | EP | disclosed |
| EP-3851447-B1 | METHODS, COMPOUNDS, COMPOSITIONS AND VEHICLES FOR DELIVERING 3-AMINO-1-PROPANESULFONIC ACID | BELLUS HEALTH INC (CA) | 2023-09-06 | — | — | EP | disclosed |
| EP-3119911-B1 | COMPOUNDS FOR USE IN TREATING ALZHEIMER'S DISEASE IN APOE4+/+ PATIENTS | ALZHEON INC (US) | 2023-08-09 | — | — | EP | disclosed |
| US-20230087041-A1 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | ALZHEON, INC. | 2023-03-23 | — | — | US | disclosed |
| US-20210386693-A1 | METHODS, COMPOUNDS, COMPOSITIONS AND VEHICLES FOR DELIVERING 3-AMINO-1-PROPANESULFONIC ACID | BELLUS HEALTH (INTERNATIONAL) LIMITED (CH) | 2021-12-16 | — | — | US | disclosed |
| EP-3119911-A2 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | Alzheon, Inc. (US) | 2017-01-25 | — | — | EP | disclosed |
| US-9499480-B2 | Methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid | BHI LIMITED PARTNERSHIP (CA) | 2016-11-22 | — | — | US | disclosed |
| WO-2015143447-A2 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | ALZHEON, INC. (US) | 2015-09-24 | — | — | WO | disclosed |
| EP-2862581-A2 | Methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid | BHI Limited Partnership (CA) | 2015-04-22 | — | — | EP | disclosed |
| EP-2089417-B1 | METHODS, COMPOUNDS, COMPOSITIONS AND VEHICLES FOR DELIVERING 3-AMINO-1-PROPANESULFONIC ACID | BHI LTD PARTNERSHIP (CA) | 2014-12-31 | — | — | EP | disclosed |
| US-20140220122-A1 | METHODS, COMPOUNDS, COMPOSITIONS AND VEHICLES FOR DELIVERING 3-AMINO-1-PROPANESULFONIC ACID | BHI LIMITED PARTNERSHIP (CA) | 2014-08-07 | — | — | US | disclosed |
| US-8748656-B2 | Methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid | BHI LIMITED PARTNERSHIP (CA) | 2014-06-10 | — | — | US | disclosed |
| US-20080146642-A1 | Propanesulfonic acid amino acid prodrugs that can deliver 3-amino-1-propanesulfonic acid (3APS) by minimizing metabolism associated with that drug, particularly compounds that block or protect amino group of 3APS such that it avoids metabolism by transaminases or monoamine oxidase; Alzheimer's disease | BELLUS HEALTH INC. (CA) | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240065990-A1 | METHODS, COMPOUNDS, COMPOSITIONS AND VEHICLES FOR DELIVERING 3-AMINO-1-PROPANESULFONIC ACID | APP, PSEN1, PSEN2 | KMT2A 3091/4885ALOX15 1882/4885BLM 4527/4885 |
| US-20210386693-A1 | METHODS, COMPOUNDS, COMPOSITIONS AND VEHICLES FOR DELIVERING 3-AMINO-1-PROPANESULFONIC ACID | APP, PSEN1, PSEN2 | KMT2A 3162/4885ALOX15 1998/4885BLM 4559/4885 |
| US-20230087041-A1 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | ACHE, PSEN2, PSEN1 | KMT2A 1777/4885ALOX15 676/4885BLM 2367/4885 |
| US-20080146642-A1 | Propanesulfonic acid amino acid prodrugs that can deliver 3-amino-1-propanesulfonic acid (3APS) by minimizing metabolism associated with that drug, particularly compounds that block or protect amino group of 3APS such that it avoids metabolism by transaminases or monoamine oxidase; Alzheimer's disease | DNPEP, DAO, APP | KMT2A 2014/4885ALOX15 1144/4885BLM 4691/4885 |
| US-20140220122-A1 | METHODS, COMPOUNDS, COMPOSITIONS AND VEHICLES FOR DELIVERING 3-AMINO-1-PROPANESULFONIC ACID | APP, PSEN1, PSEN2 | KMT2A 3162/4885ALOX15 1998/4885BLM 4559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.