SCHEMBL498912

SCHEMBL498912

Fc1ccsc1-c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.41
TP53 P04637 1/20 0.41
ALOX15 P16050 1/20 0.41
MAPK1 P28482 1/20 0.41
KMT2A Q03164 1/20 0.41
PDPK1 O15530 1/20 0.40
ALDH1A1 P00352 1/20 0.36
MAPK14 Q16539 1/20 0.36
CASP3 P42574 1/20 0.36
SLC22A2 O15244 1/20 0.36
SLC22A1 O15245 1/20 0.36
SLC22A3 O75751 1/20 0.36
SLC6A4 P31645 1/20 0.36
PTGS1 P23219 4/20 0.35
CYP2E1 P05181 1/20 0.34
CYP2A6 P11509 1/20 0.34
CYP2B6 P20813 1/20 0.34
PTPRC P08575 1/20 0.34
KDM4E B2RXH2 1/20 0.34
BCAT2 O15382 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19472353 0.79 ESR1 (0.40) PTGS2MAPK14PTGS1CYP2A6CYP2B6
SCHEMBL1681771 0.73 PTGS2 (0.65) PTGS2MAPK14PTGS1PTPRCBCAT2
SCHEMBL1821918 0.71 CYP2A6 (0.60) PTGS2TP53ALOX15MAPK1KMT2A
Ammonia Solution, Strong SCHEMBL28994523 0.71 PTGS2 (0.62) PTGS2MAPK14PTGS1PTPRCBCAT2
SCHEMBL544880 0.71 TDO2 (0.42) PTGS2TP53ALOX15MAPK1KMT2A
SCHEMBL2782853 0.71 PTGS2 (0.68) PTGS2MAPK14PTGS1BCAT2
SCHEMBL519565 0.71 MAPK1 (0.44) PTGS2TP53ALOX15MAPK1KMT2A
SCHEMBL1895888 0.71 CASP3 (0.56) PTGS2TP53ALOX15MAPK1KMT2A
SCHEMBL22157985 0.71 TP53 (0.44) PTGS2TP53ALOX15MAPK1KMT2A
SCHEMBL17227441 0.71 KMT2A (0.41) PTGS2TP53ALOX15MAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11623226-B2 Polymerized metal catalyst air cleaner AMERICAIR CORPORATION (CA) 2023-04-11 US claimed
US-20220168751-A1 Polymerized Metal Catalyst Air Cleaner AMERICAIR CORPORATION (CA) 2022-06-02 US claimed
US-11285491-B2 Polymerized metal catalyst air cleaner AMERICAIR CORPORATION (CA) 2022-03-29 US claimed
US-20200368758-A1 Polymerized Metal Catalyst Air Cleaner AMERICAIR CORPORATION (CA) 2020-11-26 US claimed
CN-102881866-B A kind of lead carbon battery negative plate containing lead graphene composite material 浙江南都电源动力股份有限公司 2017-03-01 CN claimed
CN-104987320-A Preparation method of canagliflozin intermediates CANGZHOU SENARY CHEMICAL SCIENCE TEC CO LTD 2015-10-21 CN claimed
CN-104681792-A Negative plate additive for lead storage battery NO 63971 TROOPS PLA 2015-06-03 CN claimed
CN-103515579-A Negative plate of lead storage battery NO 63971 TROOPS PLA 2014-01-15 CN claimed
US-8359105-B2 Electrically conductive pathways in medical devices BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-01-22 US claimed
CN-102881866-A Lead-carbon battery negative plate containing lead and graphene composite materials ZHEJIANG NARADA POWER SOURCE 2013-01-16 CN claimed
CN-201655911-U Carbonaceous electrode plate of lead-acid battery 63971 FORCES PLA 2010-11-24 CN claimed
WO-2010027426-A2 ELECTRICALLY CONDUCTIVE PATHWAYS IN MEDICAL DEVICES BOSTON SCIENTIFIC SCIMED, INC. (US) 2010-03-11 WO claimed
US-20100057174-A1 ELECTRICALLY CONDUCTIVE PATHWAYS IN MEDICAL DEVICES BOSTON SCIENTIFIC SCIMED, INC. (US) 2010-03-04 US claimed
EP-1666086-B1 Automatic capture pacing lead PACESETTER INC (US) 2008-04-30 EP claimed
US-20060122681-A1 Automatic capture pacing lead PACESETTER, INC. 2006-06-08 US claimed
EP-1666086-A1 Automatic capture pacing lead Pacesetter, Inc. (US) 2006-06-07 EP claimed
US-6999821-B2 Body implantable lead including one or more conductive polymer electrodes and methods for fabricating same PACESETTER, INC. (US) 2006-02-14 US claimed
US-20030139794-A1 Body implantable lead including one or more conductive polymer electrodes and methods for fabricating same PACESETTER, INC. 2003-07-24 US claimed
US-11710827-B2 Method for the preparation of an electrode comprising an aluminium substrate, aligned carbon nanotubes and an electroconductive organic polymer, the electrode and uses thereof CY CERGY PARIS UNIVERSITÉ (FR) 2023-07-25 US disclosed
US-5733683-A ELECTROCONDUCTIVE POLYMER OF FLUOROPHENYL POLYTHIOPHENE FOR ELECTROLYTIC CELLS THE JOHNS HOPKINS UNIVERSITY (US) 1998-03-31 US disclosed