Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2011068 | 0.81 | KCNH2 (0.50) | TDO2ALDH1A1HSD17B10MAPTKMT2A | |
| SCHEMBL27662362 | 0.80 | MEN1 (0.51) | ALDH1A1HSD17B10MAPTKMT2AMAPK1 | |
| SCHEMBL4952546 | 0.79 | CYP3A4 (0.50) | ALDH1A1HSD17B10MAPTCYP1A2CYP2D6 | |
| SCHEMBL3715393 | 0.79 | CES1 (0.39) | ALDH1A1HSD17B10MAPTKMT2AALOX15 | |
| SCHEMBL7457943 | 0.77 | CASP3 (0.41) | ALDH1A1HSD17B10MAPTCYP1A2KMT2A | |
| SCHEMBL8289756 | 0.77 | PTGS1 (0.31) | PTGS2 | |
| SCHEMBL7461445 | 0.77 | PTGS2 (0.46) | ALDH1A1HSD17B10MAPTCYP2C19ALOX15 | |
| SCHEMBL4197618 | 0.77 | MAPK14 (0.50) | ALDH1A1HSD17B10CYP1A2CYP2C19PTGS2 | |
| SCHEMBL17227441 | 0.76 | KMT2A (0.41) | TDO2ALDH1A1MAPTCYP1A2CYP2D6 | |
| SCHEMBL13617123 | 0.76 | ALDH1A1 (0.45) | ALDH1A1HSD17B10MAPTKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119411112-A | Surface treatment method for improving corrosion resistance of steel surface | 佛山市义众金属材料有限公司 | 2025-02-11 | — | — | CN | claimed |
| US-11121327-B2 | Spiro-condensed lactam compounds for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2021-09-14 | — | — | US | disclosed |
| US-20200208285-A1 | ELECTROLYTIC SN OR SN ALLOY PLATING SOLUTION AND METHOD FOR PRODUCING SN OR SN ALLOY PLATED ARTICLE | UEMURA KOGYO KK (JP) | 2020-07-02 | — | — | US | disclosed |
| US-9708340-B2 | Urea derivatives and their use as fatty-acid binding protein (FABP) inhibitors | HOFFMANN-LA ROCHE INC. (US) | 2017-07-18 | — | — | US | disclosed |
| US-20160372681-A1 | SPIRO-CONDENSED LACTAM COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-12-22 | — | — | US | disclosed |
| US-20160185795-A1 | UREA DERIVATIVES AND THEIR USE AS FATTY-ACID BINDING PROTEIN (FABP) INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 2016-06-30 | — | — | US | disclosed |
| US-8980837-B2 | Inhibitors of IAP | GENENTECH, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| US-8980837-B2 | Inhibitors of IAP | GENENTECH, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| US-8980837-B2 | Inhibitors of IAP | GENENTECH, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| EP-1778718-B1 | INHIBITORS OF IAP | GENENTECH INC (US) | 2014-10-08 | — | — | EP | disclosed |
| US-7244851-B2 | 1-[2-Cyclohexyl-2-(2-methylamino-propionylamino)-acetyl]-pyrrolidine-2-carboxylic acid (2-phenyl-2H-pyrazol-3-yl)-amide; inhibitors of IAP, for treating malignancies | GENENTECH, INC. (US) | 2007-07-17 | — | — | US | disclosed |
| US-7244851-B2 | 1-[2-Cyclohexyl-2-(2-methylamino-propionylamino)-acetyl]-pyrrolidine-2-carboxylic acid (2-phenyl-2H-pyrazol-3-yl)-amide; inhibitors of IAP, for treating malignancies | GENENTECH, INC. (US) | 2007-07-17 | — | — | US | disclosed |
| EP-1778718-A1 | INHIBITORS OF IAP | Genentech, Inc. (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006014361-A1 | INHIBITORS OF IAP | GENENTECH, INC. (US) | 2006-02-09 | — | — | WO | disclosed |
| US-20060014700-A1 | 1-[2-Cyclohexyl-2-(2-methylamino-propionylamino)-acetyl]-pyrrolidine-2-carboxylic acid (2-phenyl-2H-pyrazol-3-yl)-amide; inhibitors of IAP, for treating malignancies | GENENTECH, INC. (US) | 2006-01-19 | — | — | US | disclosed |
| EP-0737682-B1 | Substituted thiophene derivative and agricultural and horticultural fungicide containing the same as active ingredient | MITSUI CHEMICALS INC (JP) | 2002-01-09 | — | — | EP | disclosed |
| CN-1061657-C | Substituted thiophene derivative and agricultural and horticultural fungicide containing the same as active ingredient | MITSUI TOATSU CHEMICALS (JP) | 2001-02-07 | — | — | CN | disclosed |
| US-5747518-A | EFFECTIVE AGAINST CHEMICAL RESISTANT FUNGI; NONPHYTOTOXIC TO CROPS | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-05-05 | — | — | US | disclosed |
| CN-1146993-A | Substituted thiophene derivative and agricultural and horticultural fungicide containing the same as active ingredient | MITSUI TOATSU CHEMICALS (JP) | 1997-04-09 | — | — | CN | disclosed |
| EP-0737682-A1 | Substituted thiophene derivative and agricultural and horticultural fungicide containing the same as active ingredient | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1996-10-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185795-A1 | UREA DERIVATIVES AND THEIR USE AS FATTY-ACID BINDING PROTEIN (FABP) INHIBITORS | FABP1, FABP5, FABP2 | TDO2 4272/4885ALDH1A1 689/4885HSD17B10 900/4885 |
| US-11121327-B2 | Spiro-condensed lactam compounds for organic electroluminescent devices | PORCN, COASY, AAAS | TDO2 4016/4885ALDH1A1 2105/4885HSD17B10 1772/4885 |
| US-20060014700-A1 | 1-[2-Cyclohexyl-2-(2-methylamino-propionylamino)-acetyl]-pyrrolidine-2-carboxylic acid (2-phenyl-2H-pyrazol-3-yl)-amide; inhibitors of IAP, for treating malignancies | BIRC5, BIRC2, XIAP | TDO2 3929/4885ALDH1A1 2930/4885HSD17B10 4602/4885 |
| US-20160372681-A1 | SPIRO-CONDENSED LACTAM COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | PORCN, COASY, AAAS | TDO2 4016/4885ALDH1A1 2105/4885HSD17B10 1772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.