Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CLPP | Q16740 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4992359 | 0.90 | MEN1 (0.41) | MEN1KMT2APOLBNOD1CLPP | |
| SCHEMBL4992456 | 0.89 | MEN1 (0.40) | MEN1KMT2ALMNAPOLBNOD1 | |
| SCHEMBL4988549 | 0.89 | GRM2 (0.43) | MEN1KMT2ALMNASMN1; SMN2NOD1 | |
| SCHEMBL4984714 | 0.89 | KMT2A (0.44) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL4989469 | 0.88 | GRM2 (0.40) | MEN1KMT2AGRM2 | |
| SCHEMBL4989370 | 0.88 | ALDH1A1 (0.43) | MEN1KMT2ALMNANOD1KDM4E | |
| SCHEMBL4980850 | 0.88 | OPRM1 (0.39) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL4985321 | 0.88 | CFTR (0.44) | POLBSMN1; SMN2NOD1CLPPMAPT | |
| SCHEMBL4985463 | 0.88 | GRM2 (0.39) | MEN1KMT2AKDM4ECLPPGRM2 | |
| SCHEMBL4986796 | 0.87 | MEN1 (0.44) | MEN1KMT2ALMNASMN1; SMN2NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080039478-A1 | Bicycloheteroaryl Compounds as P2X7 Modulators and Uses Thereof | RENOVIS, INC. | 2008-02-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039478-A1 | Bicycloheteroaryl Compounds as P2X7 Modulators and Uses Thereof | P2RX7, P2RX3, P2RX2 | MEN1 4853/4885KMT2A 4614/4885LMNA 1911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.