Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | PPARG | P37231 | 5/20 | 0.42 |
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14342743 | 0.93 | MAPT (0.47) | MAPTTP53PPARGPPARACYP2C9 | |
| SCHEMBL14071895 | 0.93 | TP53 (0.47) | MAPTTP53PPARGPPARACYP2C9 | |
| SCHEMBL339515 | 0.93 | TP53 (0.47) | MAPTTP53PPARGPPARACYP2C9 | |
| SCHEMBL30529086 | 0.93 | TP53 (0.47) | MAPTTP53PPARGPPARACYP2C9 | |
| SCHEMBL181098 | 0.93 | TP53 (0.47) | MAPTTP53PPARGPPARACYP2C9 | |
| SCHEMBL2917013 | 0.87 | TP53 (0.46) | MAPTTP53PPARGPPARACYP2C9 | |
| SCHEMBL2523252 | 0.86 | PPARA (0.45) | MAPTTP53PPARGPPARACYP2C9 | |
| SCHEMBL2523255 | 0.86 | PPARA (0.45) | MAPTTP53PPARGPPARACYP2C9 | |
| SCHEMBL2518436 | 0.85 | FFAR1 (0.52) | MAPTTP53PPARGPPARAFFAR1 | |
| SCHEMBL2518434 | 0.85 | FFAR1 (0.52) | MAPTTP53PPARGPPARAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221336-A1 | Pparalpha/Gamma Agonists and Processes of Preparing | GARRETT CHRISTINE E | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221336-A1 | Pparalpha/Gamma Agonists and Processes of Preparing | PPARA, PPARG, PPARD | MAPT 4884/4885TP53 3482/4885PPARG 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.