Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LONP1 | P36776 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.44 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.44 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.44 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.44 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.44 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.44 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.44 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.44 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.44 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4990235 | 0.83 | ALDH1A1 (0.42) | SMN1; SMN2HTTNPC1RAB9APOLB | |
| SCHEMBL4990580 | 0.83 | ACACB (0.49) | SMN1; SMN2HTTNPC1RAB9ATP53 | |
| SCHEMBL4988590 | 0.80 | XIAP (0.40) | KDM4EKMT2AMAPT | |
| SCHEMBL4985552 | 0.80 | TRPA1 (0.41) | NPSR1MAPK1MAPT | |
| SCHEMBL4985300 | 0.79 | HCAR3 (0.45) | KDM4EMAPK1MAPT | |
| SCHEMBL4988913 | 0.79 | CHRM2 (0.39) | KMT2AMAPT | |
| SCHEMBL4991288 | 0.79 | CHRM2 (0.39) | — | |
| SCHEMBL21968828 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2HTTLONP1NPC1RAB9A | |
| SCHEMBL21968898 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2HTTLONP1NPC1RAB9A | |
| SCHEMBL30786951 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2HTTLONP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080125409-A1 | 1,5-Diheterocycle-1H-Triazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-05-29 | — | — | US | disclosed |
| EP-1803719-A1 | 1,5-DIHETEROCYCLE-1H-TRIAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080125409-A1 | 1,5-Diheterocycle-1H-Triazole Derivative | PTGS1, PTGER1, TBXA2R | SMN1; SMN2 3713/4885HTT 3347/4885LONP1 1194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.