Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | FUT8 | Q9BYC5 | 1/20 | 0.42 |
| ▸ | CD40 | P25942 | 1/20 | 0.40 |
| ▸ | CD40LG | P29965 | 1/20 | 0.40 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4991193 | 1.00 | PRMT1 (0.48) | PRMT1ENPP2CYP1A2CA2CA3 | |
| SCHEMBL13880703 | 0.93 | PRMT1 (0.48) | PRMT1ENPP2CYP1A2CA2CA3 | |
| SCHEMBL14495438 | 0.91 | PRMT1 (0.51) | PRMT1ENPP2CYP1A2CYP2C9MAPK1 | |
| SCHEMBL28482747 | 0.89 | CA2 (0.45) | PRMT1ENPP2CYP1A2CA2CA3 | |
| SCHEMBL13880701 | 0.88 | PRMT1 (0.46) | PRMT1ENPP2CYP1A2CA2CA3 | |
| SCHEMBL13880575 | 0.88 | ENPP2 (0.47) | PRMT1ENPP2CYP1A2CA2CA3 | |
| SCHEMBL13880604 | 0.87 | CA2 (0.49) | PRMT1ENPP2CYP1A2CA2CA3 | |
| SCHEMBL13880599 | 0.86 | ENPP2 (0.46) | PRMT1ENPP2CYP1A2CA2CA3 | |
| SCHEMBL2897652 | 0.85 | THRB (0.55) | PRMT1ENPP2CYP1A2CA2CA3 | |
| SCHEMBL13892241 | 0.85 | ENPP2 (0.46) | PRMT1ENPP2CYP1A2CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373868-B1 | IMPROVED AFFINITY MATRICES WITH ENHANCED VISIBILITY FOR MOLECULAR PULL-DOWN AND IMMUNOPRECIPITATION APPLICATIONS | SIGMA ALDRICH CO LLC (US) | 2015-05-20 | — | — | EP | claimed |
| EP-1373868-A4 | IMPROVED AFFINITY MATRICES WITH ENHANCED VISIBILITY FOR MOLECULAR PULL-DOWN AND IMMUNOPRECIPITATION APPLICATIONS | SIGMA ALDRICH CO (US) | 2006-11-29 | — | — | EP | claimed |
| US-6887377-B2 | Affinity matrices with enhanced visibility for molecular pull-down and immunoprecipitation applications | SIGMA-ALDRICH CO. (US) | 2005-05-03 | — | — | US | claimed |
| EP-1373868-A1 | IMPROVED AFFINITY MATRICES WITH ENHANCED VISIBILITY FOR MOLECULAR PULL-DOWN AND IMMUNOPRECIPITATION APPLICATIONS | Sigma-Aldrich Co. (US) | 2004-01-02 | — | — | EP | claimed |
| US-20020108908-A1 | Affinity matrices with enhanced visibility for molecular pull-down and immunoprecipitation applications | SIGMA-ALDRICH CO. | 2002-08-15 | — | — | US | claimed |
| WO-2002061406-A1 | IMPROVED AFFINITY MATRICES WITH ENHANCED VISIBILITY FOR MOLECULAR PULL-DOWN AND IMMUNOPRECIPITATION APPLICATIONS | SIGMA-ALDRICH CO. (US) | 2002-08-08 | — | — | WO | claimed |
| EP-1373868-B1 | IMPROVED AFFINITY MATRICES WITH ENHANCED VISIBILITY FOR MOLECULAR PULL-DOWN AND IMMUNOPRECIPITATION APPLICATIONS | SIGMA ALDRICH CO LLC (US) | 2015-05-20 | — | — | EP | disclosed |
| US-7438806-B2 | Affinity matrices with enhanced visibility for molecular pull-down and immunoprecipitation applications | SIGMA-ALDRICH CO. (US) | 2008-10-21 | — | — | US | disclosed |
| US-20070048800-A1 | Affinity matrices with enhanced visibility for molecular pull-down and immunoprecipitation applications | SIGMA-ALDRICH CO. (US) | 2007-03-01 | — | — | US | disclosed |
| US-7163633-B2 | Affinity matrices with enhanced visibility for molecular pull-down and immunoprecipitation applications | SIGMA-ALDRICH CO. (US) | 2007-01-16 | — | — | US | disclosed |
| EP-1373868-A4 | IMPROVED AFFINITY MATRICES WITH ENHANCED VISIBILITY FOR MOLECULAR PULL-DOWN AND IMMUNOPRECIPITATION APPLICATIONS | SIGMA ALDRICH CO (US) | 2006-11-29 | — | — | EP | disclosed |
| US-6887377-B2 | Affinity matrices with enhanced visibility for molecular pull-down and immunoprecipitation applications | SIGMA-ALDRICH CO. (US) | 2005-05-03 | — | — | US | disclosed |
| US-20050079554-A1 | Affinity matrices with enhanced visibility for molecular pull-down and immunoprecipitation applications | SIGMA-ALDRICH CO. | 2005-04-14 | — | — | US | disclosed |
| EP-1373868-A1 | IMPROVED AFFINITY MATRICES WITH ENHANCED VISIBILITY FOR MOLECULAR PULL-DOWN AND IMMUNOPRECIPITATION APPLICATIONS | Sigma-Aldrich Co. (US) | 2004-01-02 | — | — | EP | disclosed |
| US-20020108908-A1 | Affinity matrices with enhanced visibility for molecular pull-down and immunoprecipitation applications | SIGMA-ALDRICH CO. | 2002-08-15 | — | — | US | disclosed |
| WO-2002061406-A1 | IMPROVED AFFINITY MATRICES WITH ENHANCED VISIBILITY FOR MOLECULAR PULL-DOWN AND IMMUNOPRECIPITATION APPLICATIONS | SIGMA-ALDRICH CO. (US) | 2002-08-08 | — | — | WO | disclosed |