Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GRK2 | P25098 | 1/20 | 0.45 |
| ▸ | PLEC | Q15149 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29383259 | 0.92 | THRB (0.57) | THRBMEN1KMT2APOLBGRK2 | |
| SCHEMBL4991205 | 0.85 | PRMT1 (0.48) | THRBMEN1KMT2AENPP2CA2 | |
| SCHEMBL4991193 | 0.85 | PRMT1 (0.48) | THRBMEN1KMT2AENPP2CA2 | |
| SCHEMBL29637793 | 0.83 | THRB (0.48) | THRBMEN1KMT2APOLBGRK2 | |
| SCHEMBL2898227 | 0.81 | THRB (0.54) | THRBMEN1KMT2APOLBGRK2 | |
| SCHEMBL29404912 | 0.79 | ENPP2 (0.51) | THRBMEN1KMT2APOLBGRK2 | |
| SCHEMBL13880703 | 0.79 | PRMT1 (0.48) | THRBMEN1KMT2APOLBGRK2 | |
| SCHEMBL28482747 | 0.78 | CA2 (0.45) | THRBMEN1KMT2AENPP2CA2 | |
| SCHEMBL28343203 | 0.77 | USP2 (0.52) | THRBMEN1KMT2APOLBGRK2 | |
| SCHEMBL4807909 | 0.76 | PTPN1 (0.57) | THRBMEN1KMT2APOLBGRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2189503-A1 | NOVEL NUCLEIC ACID DERIVATIVE INTO WHICH GIVEN COMPOUND HAS BEEN INTRODUCED AND METHOD FOR PRODUCING THE SAME | Biodynamics Laboratory, INC. (JP) | 2010-05-26 | — | — | EP | disclosed |
| US-20090090628-A1 | NUCLEIC ACID DERIVATIVES AND METHODS OF USE | BIODYNAMICS LABORATORY, INC (JP) | 2009-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090090628-A1 | NUCLEIC ACID DERIVATIVES AND METHODS OF USE | NSUN3, TRDMT1, NSUN2 | THRB 2493/4885MEN1 2655/4885KMT2A 2066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.