SCHEMBL499141

SCHEMBL499141

c1csc(-c2ccc(-c3cccs3)o2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.53
KDM4E B2RXH2 6/20 0.53
HPGD P15428 5/20 0.53
MAPT P10636 3/20 0.53
TDP1 Q9NUW8 3/20 0.53
HSD17B10 Q99714 3/20 0.53
CACNA1B Q00975 1/20 0.53
APBA1 Q02410 1/20 0.53
S1PR4 O95977 1/20 0.46
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
NPC1 O15118 5/20 0.44
RAB9A P51151 5/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
CASP3 P42574 2/20 0.42
SENP7 Q9BQF6 2/20 0.42
LMNA P02545 1/20 0.42
LTA4H P09960 2/20 0.42
QPCT Q16769 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28879176 0.87 ALDH1A1 (0.49) ALDH1A1KDM4EHPGDMAPTTDP1
SCHEMBL3348926 0.84 S1PR4 (0.48) ALDH1A1KDM4EHPGDMAPTTDP1
SCHEMBL18876413 0.84 ALDH1A1 (0.46) ALDH1A1KDM4EHPGDMAPTTDP1
SCHEMBL13140527 0.82 ALDH1A1 (0.42) ALDH1A1KDM4EHPGDMAPTTDP1
SCHEMBL22945653 0.81 ALDH1A1 (0.44) ALDH1A1KDM4EHPGDMAPTTDP1
SCHEMBL13801136 0.81 KDM4E (0.44) ALDH1A1KDM4EHPGDMAPTTDP1
SCHEMBL21790195 0.81 ALDH1A1 (0.41) ALDH1A1KDM4EHPGDMAPTTDP1
SCHEMBL9048215 0.80 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDMAPTTDP1
SCHEMBL18879678 0.80 KDM4E (0.46) ALDH1A1KDM4EHPGDMAPTTDP1
SCHEMBL10287183 0.80 KDM4E (0.58) ALDH1A1KDM4EHPGDMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12358871-B2 Photochemical synthesis of vitamin D3 using sensitizers FERMENTA BIOTECH LIMITED (IN) 2025-07-15 US claimed
US-20220372065-A1 SYNTHESIS OF CHOLESTEROL AND VITAMIN D3 FROM PHYTOSTEROLS FERMENTA BIOTECH LIMITED (IN) 2022-11-24 US claimed
US-20220298106-A1 IMPROVED PHOTOCHEMICAL SYNTHESIS OF VITAMIN D3 USING SENSITIZERS FERMENTA BIOTECH LIMITED (IN) 2022-09-22 US claimed
US-20220372065-A1 SYNTHESIS OF CHOLESTEROL AND VITAMIN D3 FROM PHYTOSTEROLS FERMENTA BIOTECH LIMITED (IN) 2022-11-24 US disclosed
EP-2379109-B1 COMBINATION OF PHOTODYNAMIC THERAPY AND ANTI-VEGF AGENTS IN THE TREATMENT OF UNWANTED CHOROIDAL NEOVASCULATURE BAUSCH HEALTH COMPANIES INC (CA) 2020-10-07 EP disclosed
US-9226917-B2 Photodynamic therapy for conditions of the eye VALEANT PHARMACEUTICALS INTERNATIONAL, INC. (CA) 2016-01-05 US disclosed
US-8968715-B2 Drug delivery systems for photodynamic therapy THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2015-03-03 US disclosed
US-8852629-B2 Drug delivery system for hydrophobic drugs VALEANT PHARMACEUTICALS INTERNATIONAL, INC. (CA) 2014-10-07 US disclosed
EP-1357912-B9 PHOTODYNAMIC THERAPY OF OCCULT CHOROIDAL NEOVASCULARIZATION LINKED TO AGE-RELATED MACULAR DEGENERATION QUADRA LOGIC TECH INC (CA) 2012-06-13 EP disclosed
EP-1357912-B1 PHOTODYNAMIC THERAPY OF OCCULT CHOROIDAL NEOVASCULARIZATION LINKED TO AGE-RELATED MACULAR DEGENERATION QUADRA LOGIC TECH INC (CA) 2012-04-25 EP disclosed
US-20120041356-A1 PHOTODYNAMIC THERAPY FOR CONDITIONS OF THE EYE QLT INC. (CA) 2012-02-16 US disclosed
WO-2001035996-A2 USE OF PDT TO INHIBIT INTIMAL HYPERPLASIA QLT INC. (CA) 2001-05-25 WO disclosed
WO-2001035997-A2 USE OF LOW-DOSE PDT TO INHIBIT RESTENOSIS QLT INC. (CA) 2001-05-25 WO disclosed
US-6184540-B1 SEMICONDUCTOR HAVING A LAYER OF A POLYTHIOPHENE DERIVED FROM A SOLUBLE PRECURSOR COMPOUND OF TETRAHYDROTHIOPHENE OR TETRAHYDROFURAN UNITS HAVING THERMALLY SEPARABLE ARYL- OR ALKYL-THIO SUBSTITUENTS, WHICH CAN BE PROCESSED FROM SOLUTION U.S. PHILIPS CORPORATION 2001-02-06 US disclosed
US-6124475-A Method of preparing a thiophene-containing or furan-containing conjugated compound and precursor compound used therein U.S. PHILIPS CORPORATION (US) 2000-09-26 US disclosed
US-5919951-A Method of preparing a thiophene-containing or furan-containing conjugated compound and precursor compound used therein U.S. PHILIPS CORPORATION (US) 1999-07-06 US disclosed
EP-0867437-A1 \"Method of preparing a thiophene-containing or furan -containing conjugated compound and precursor compound used therein\". Koninklijke Philips Electronics N.V. (NL) 1998-09-30 EP disclosed
EP-0454204-B1 Method for the photochemical isomeration of organic compounds under the influence of a photosensitizer DUPHAR INT RES (NL) 1995-06-28 EP disclosed
US-5252191-A Method for the photochemical isomerization of organic compounds under the influence of a photosensitizer DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1993-10-12 US disclosed
EP-0454204-A2 Method for the photochemical isomeration of organic compounds under the influence of a photosensitizer DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1991-10-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220372065-A1 SYNTHESIS OF CHOLESTEROL AND VITAMIN D3 FROM PHYTOSTEROLS CYP2R1, CYP46A1, CYP24A1 ALDH1A1 2914/4885KDM4E 1043/4885HPGD 181/4885
US-12358871-B2 Photochemical synthesis of vitamin D3 using sensitizers CYP2R1, CYP24A1, VDR ALDH1A1 651/4885KDM4E 3208/4885HPGD 122/4885
US-20220298106-A1 IMPROVED PHOTOCHEMICAL SYNTHESIS OF VITAMIN D3 USING SENSITIZERS CYP2R1, CYP24A1, CYP27B1 ALDH1A1 777/4885KDM4E 3253/4885HPGD 177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.