SCHEMBL498533

SCHEMBL498533

COc1cc(-c2c3nc(c(-c4cc(OC)c(OC)c(OC)c4)c4ccc([nH]4)c(-c4cc(OC)c(OC)c(OC)c4)c4nc(c(-c5cc(OC)c(OC)c(OC)c5)c5ccc2[nH]5)C=C4)C=C3)cc(OC)c1OC

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 3/20 0.49
▸ ABCG2 Q9UNQ0 1/20 0.46
▸ TOP1 P11387 4/20 0.44
▸ CYCS P99999 3/20 0.43
▸ ENPP2 Q13822 1/20 0.42
▸ KDM4E B2RXH2 2/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ GAA P10253 1/20 0.42
▸ MPI P34949 1/20 0.42
▸ APOBEC3G Q9HC16 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42
▸ BRD4 O60885 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ TSHR P16473 1/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29888944 1.00 TERT (0.49) TERTABCG2TOP1CYCSENPP2
SCHEMBL30679527 0.86 TERT (0.48) TERTABCG2TOP1CYCSENPP2
SCHEMBL22473799 0.85 TOP1 (0.54) ABCG2TOP1CYCSENPP2KMT2A
SCHEMBL29441514 0.84 ABCG2 (0.49) TERTABCG2TOP1CYCSENPP2
SCHEMBL30616085 0.84 ABCG2 (0.49) TERTABCG2TOP1CYCSENPP2
SCHEMBL499168 0.84 ABCG2 (0.49) TERTABCG2TOP1CYCSENPP2
SCHEMBL2950389 0.83 STAT3 (0.54) TERTABCG2KDM4EALDH1A1GAA
SCHEMBL498495 0.81 TERT (0.51) TERTABCG2TOP1CYCSENPP2
SCHEMBL29408468 0.81 TERT (0.51) TERTABCG2TOP1CYCSENPP2
SCHEMBL2694939 0.81 NOX1 (0.49) TERTABCG2TOP1CYCSENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9867800-B2 Method of quenching singlet and triplet excited states of pigments, such as porphyrin compounds, particularly protoporphyrin IX, with conjugated fused tricyclic compounds have electron withdrawing groups, to reduce generation of reactive oxygen species, particularly singlet oxygen HALLSTAR INNOVATIONS CORP. (US) 2018-01-16 — — US claimed
US-20150164852-A1 METHOD OF QUENCHING SINGLET AND TRIPLET EXCITED STATES OF PIGMENTS, SUCH AS PORPHYRIN COMPOUNDS, PARTICULARLY PROTOPORPHYRIN IX, WITH CONJUGATED FUSED TRICYCLIC COMPOUNDS HAVE ELECTRON WITHDRAWING GROUPS, TO REDUCE GENERATION OF REACTIVE OXYGEN SPECIES, PARTICULARLY SINGLET OXYGEN HALLSTAR INNOVATIONS CORP. (US) 2015-06-18 — — US claimed
WO-2014025370-A1 TRICYCLIC ENERGY QUENCHER COMPOUNDS FOR REDUCING SINGLET OXYGEN GENERATION HALLSTAR INNOVATIONS CORP. (US) 2014-02-13 — — WO claimed
US-6010805-A Ion conducting electrolyte material containing a lithium porphyrin complex UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2000-01-04 — — US claimed
US-12546743-B2 Electrochemical sensor and related methods UNIVERSITY OF SOUTH FLORIDA (US) 2026-02-10 — — US disclosed
US-12071498-B2 Radically polymerizable compositions Polynt Composites USA, Inc. (US) 2024-08-27 — — US disclosed
CN-113474383-B Free radical polymerizable composition 波林复合材料美国股份有限公司 2023-10-31 — — CN disclosed
US-20230296554-A1 ELECTROCHEMICAL SENSOR AND RELATED METHODS UNIVERSITY OF SOUTH FLORIDA 2023-09-21 — — US disclosed
US-20230257500-A1 RADICALLY POLYMERIZABLE COMPOSITIONS BNY MELLON CORPORATE TRUSTEE SERVICES LIMITED, AS SECURITY AGENT (GB) 2023-08-17 — — US disclosed
US-11518834-B2 Radically polymerizable compositions Polynt Composites USA, Inc. (US) 2022-12-06 — — US disclosed
EP-3077467-B1 DRIER COMPOSITION AND USE THEREOF PPG EUROPE B V (NL) 2022-11-02 — — EP disclosed
EP-3906265-A1 RADICALLY POLYMERIZABLE COMPOSITIONS Polynt Composites USA Inc. (US) 2021-11-10 — — EP disclosed
EP-1545512-A1 METHODS FOR USING GOLD (III) COMPLEXES AS ANTI-TUMOR AND ANTI-HIV AGENTS The University of Hong Kong (CN) 2005-06-29 — — EP disclosed
US-20040266748-A1 Photosensitizing carbamate derivatives MIRAVANT PHARMACEUTICALS, INC. 2004-12-30 — — US disclosed
EP-1450790-A2 PHOTOSENSITIZING CARBAMATE DERIVATIVES Miravant Pharmaceuticals, Inc. (US) 2004-09-01 — — EP disclosed
US-20040063681-A1 Methods for using gold (III) complexes as anti-tumor and anti-HIV agents CHE CHI-MING (CN) 2004-04-01 — — US disclosed
WO-2004024146-A1 METHODS FOR USING GOLD (III) COMPLEXES AS ANTI-TUMOR AND ANTI-HIV AGENTS THE UNIVERSITY OF HONG KONG (CN) 2004-03-25 — — WO disclosed
US-6609014-B1 Use of PDT to inhibit intimal hyperplasia QLT INC. (CA) 2003-08-19 — — US disclosed
WO-2003028628-A2 PHOTOSENSITIZING CARBAMATE DERIVATIVES MIRAVANT PHARMACEUTICALS, INC. (US) 2003-04-10 — — WO disclosed
US-6010805-A Ion conducting electrolyte material containing a lithium porphyrin complex UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2000-01-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063681-A1 Methods for using gold (III) complexes as anti-tumor and anti-HIV agents HCCS, ME3, IDH1 TERT 1918/4885ABCG2 820/4885TOP1 71/4885
US-12546743-B2 Electrochemical sensor and related methods EPX, MUC1, EPCAM TERT 3462/4885ABCG2 4259/4885TOP1 4862/4885
US-20150164852-A1 METHOD OF QUENCHING SINGLET AND TRIPLET EXCITED STATES OF PIGMENTS, SUCH AS PORPHYRIN COMPOUNDS, PARTICULARLY PROTOPORPHYRIN IX, WITH CONJUGATED FUSED TRICYCLIC COMPOUNDS HAVE ELECTRON WITHDRAWING GROUPS, TO REDUCE GENERATION OF REACTIVE OXYGEN SPECIES, PARTICULARLY SINGLET OXYGEN NOX3, CBR3, CCR3 TERT 1768/4885ABCG2 2540/4885TOP1 1886/4885
US-20040266748-A1 Photosensitizing carbamate derivatives CRY1, CASP3, CRY2 TERT 1623/4885ABCG2 1974/4885TOP1 1039/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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