SCHEMBL4992347

SCHEMBL4992347

CC(=O)CSC[C@H](N)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 5/20 0.53
NOS1 P29475 3/20 0.53
NOS3 P29474 2/20 0.53
ARG1 P05089 1/20 0.50
ARG2 P78540 1/20 0.50
SLC7A5 Q01650 1/20 0.41
BHMT Q93088 3/20 0.41
GRIK1 P39086 1/20 0.41
BHMT2 Q9H2M3 1/20 0.40
KIF11 P52732 3/20 0.40
PMP22 Q01453 1/20 0.39
PTGS1 P23219 1/20 0.39
SLC7A11 Q9UPY5 1/20 0.39
ALDH1A1 P00352 1/20 0.38
ALOX15 P16050 1/20 0.38
SLC1A3 P43003 1/20 0.38
SLC1A2 P43004 1/20 0.38
SLC1A1 P43005 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4992360 1.00 NOS2 (0.53) NOS2NOS1NOS3ARG1ARG2
SCHEMBL13410552 0.85 NOS2 (0.51) NOS2NOS1NOS3ARG1ARG2
SCHEMBL14286756 0.84 NOS2 (0.38) NOS2NOS1NOS3ARG1ARG2
SCHEMBL24919549 0.84 NOS2 (0.38) NOS2NOS1NOS3ARG1ARG2
SCHEMBL10187369 0.83 NOS2 (0.50) NOS2NOS1NOS3ARG1ARG2
SCHEMBL2781165 0.82 ARG1 (0.53) NOS2NOS1NOS3ARG1ARG2
Carbocysteine SCHEMBL20854 0.82 BHMT (0.59) NOS2NOS1NOS3ARG1ARG2
SCHEMBL18788686 0.82 ARG1 (0.53) NOS2NOS1NOS3ARG1ARG2
Carbocysteine SCHEMBL6762355 0.82 BHMT (0.59) NOS2NOS1NOS3ARG1ARG2
Carbocysteine SCHEMBL69149 0.82 BHMT (0.59) NOS2NOS1NOS3ARG1ARG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3572091-B1 MODIFIED RELAXIN POLYPEPTIDES AND THEIR USES AMBRX INC (US) 2023-12-13 EP disclosed
EP-3681504-B1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN INC (US) 2023-08-23 EP disclosed
US-11573224-B2 Methods of detection using X-ray fluorescence ICAGEN, LLC (US) 2023-02-07 US disclosed
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-10877035-B2 Advanced drug development and manufacturing ICAGEN, LLC (US) 2020-12-29 US disclosed
US-20200278346-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ADJACENT ACQUISITION CO., LLC 2020-09-03 US disclosed
EP-3681504-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE Icagen, Inc. (US) 2020-07-22 EP disclosed
WO-2019055754-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN, INC. (US) 2019-03-21 WO disclosed
WO-2018204764-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION (US) 2018-11-08 WO disclosed
US-20150309021-A1 Advanced Drug Development and Manufacturing LOS ALAMOS NATIONAL SECURITY, LLC 2015-10-29 US disclosed
EP-2511844-B1 X-ray microscope XRPRO SCIENCES INC (US) 2015-08-12 EP disclosed
EP-2511844-A2 Advanced drug development and manufacturing Los Alamos National Security, LLC (US) 2012-10-17 EP disclosed
EP-2084519-B1 X-RAY FLUORESCENCE ANALYSIS METHOD LOS ALAMOS NAT SECURITY LLC (US) 2012-08-01 EP disclosed
US-20080220441-A1 Advanced drug development and manufacturing THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2008-09-11 US disclosed