SCHEMBL14286756

SCHEMBL14286756

CC(=O)CSCC(N)C(C)=O

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 5/20 0.38
NOS1 P29475 3/20 0.38
NOS3 P29474 2/20 0.38
CES2 O00748 1/20 0.38
ARG1 P05089 1/20 0.34
ARG2 P78540 1/20 0.34
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
TSHR P16473 1/20 0.31
BHMT Q93088 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24919549 1.00 NOS2 (0.38) NOS2NOS1NOS3CES2ARG1
SCHEMBL22625614 0.86 NOS2 (0.42) NOS2NOS1NOS3ARG1ARG2
SCHEMBL19628285 0.84 CYP2D6 (0.46) NOS2NOS1NOS3ARG1ARG2
SCHEMBL19628287 0.84 CYP2D6 (0.46) NOS2NOS1NOS3ARG1ARG2
SCHEMBL4992360 0.84 NOS2 (0.53) NOS2NOS1NOS3ARG1ARG2
SCHEMBL19628286 0.84 CYP2D6 (0.46) NOS2NOS1NOS3ARG1ARG2
SCHEMBL4992347 0.84 NOS2 (0.53) NOS2NOS1NOS3ARG1ARG2
SCHEMBL12421053 0.83 NOS2 (0.36) NOS2NOS1NOS3ARG1ARG2
SCHEMBL15242542 0.79 NOS2 (0.41) NOS2NOS1NOS3CES2ARG1
SCHEMBL16572561 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3638284-B1 CYCLIC PEPTIDES FOR PROTECTION AGAINST RESPIRATORY SYNCYTIAL VIRUS VIROMETIX AG (CH) 2023-08-30 EP disclosed
EP-3077410-B1 PROLINE-RICH PEPTIDES PROTECTIVE AGAINST S. PNEUMONIAE VIROMETIX AG (CH) 2021-02-03 EP disclosed
US-20160324947-A1 PROLINE-RICH PEPTIDES PROTECTIVE AGAINST S. PNEUMONIAE Universität Zürich (CH) 2016-11-10 US disclosed
WO-2015082501-A1 PROLINE-RICH PEPTIDES PROTECTIVE AGAINST S. PNEUMONIAE VIROMETIX AG (CH) 2015-06-11 WO disclosed
US-8680062-B2 System for delivering therapeutic agents into living cells and cells nuclei Deliversir Ltd. (IL) 2014-03-25 US disclosed
US-20080004234-A1 System for delivering therapeutic agents into living cells and cells nuclei SEGEV LABORATORIES LIMITED (IL) 2008-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160324947-A1 PROLINE-RICH PEPTIDES PROTECTIVE AGAINST S. PNEUMONIAE SGTA, PELP1, PRR12 NOS2 3562/4885NOS1 3607/4885NOS3 2984/4885
US-20080004234-A1 System for delivering therapeutic agents into living cells and cells nuclei RCC1, NUMA1, ACIN1 NOS2 2696/4885NOS1 3239/4885NOS3 2918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.