SCHEMBL4993147

SCHEMBL4993147

C=Cc1ccccc1C=C.CN(C)C=Cc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
TSHR P16473 1/20 0.43
RELA Q04206 1/20 0.42
NFE2L2 Q16236 3/20 0.39
TRPA1 O75762 3/20 0.39
MAOB P27338 1/20 0.38
GRM5 P41594 1/20 0.38
CHAT P28329 3/20 0.35
RECQL P46063 1/20 0.35
APP P05067 1/20 0.35
CYP3A4 P08684 1/20 0.35
GLA P06280 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL26089496 0.88 ALDH1A1 (0.58) ALDH1A1TSHRRELANFE2L2TRPA1
SCHEMBL952396 0.85 RELA (0.54) ALDH1A1RELANFE2L2TRPA1MAOB
SCHEMBL81307 0.85 RELA (0.54) ALDH1A1RELANFE2L2TRPA1MAOB
Hydrochloric Acid SCHEMBL9225053 0.83 RELA (0.52) ALDH1A1RELANFE2L2TRPA1MAOB
Water SCHEMBL27350733 0.83 RELA (0.52) ALDH1A1RELANFE2L2TRPA1MAOB
(Z)-1,2-Diphenylethene SCHEMBL10982590 0.81 ALDH1A1 (0.57) ALDH1A1TSHRRELANFE2L2TRPA1
(Z)-1,2-Diphenylethene SCHEMBL10982588 0.81 ALDH1A1 (0.57) ALDH1A1TSHRRELANFE2L2TRPA1
Styrene SCHEMBL6460073 0.79 ALDH1A1 (0.64) ALDH1A1TSHRRELANFE2L2TRPA1
SCHEMBL5804705 0.78 ALDH1A1 (0.48) ALDH1A1TSHRRELANFE2L2TRPA1
Styrene SCHEMBL5670947 0.78 ALDH1A1 (0.61) ALDH1A1TSHRRELANFE2L2TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1979300-A2 A METHOD OF TREATING AN ALDEHYDE MIXTURE, USE OF THE TREATED ALDEHYDE, AND AN ALCOHOL Shell Internationale Research Maatschappij B.V. (NL) 2008-10-15 EP disclosed
US-7385090-B2 Method of treating an aldehyde mixture, use of the treated aldehyde, and an alcohol SHELL OIL COMPANY (US) 2008-06-10 US disclosed
WO-2007090158-A2 A METHOD OF TREATING AN ALDEHYDE MIXTURE, USE OF THE TREATED ALDEHYDE, AND AN ALCOHOL SHELL OIL COMPANY (US) 2007-08-09 WO disclosed
US-20070179322-A1 In the preparation of 1,3-propylene glycol by the hydroformylation of ethylene oxide, the aqueous solution of the 3-hydroxypropionaldehyde intermediate is purified by using basic and acidic ion exchangers to remove carboxylic acid and catalytic metal residue, respectively; by-product inhibition SHELL OIL COMPANY 2007-08-02 US disclosed