SCHEMBL499363

SCHEMBL499363

COc1ccc(-c2nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n2)cc1Br

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.47
SMN1; SMN2 Q16637 6/20 0.43
ALDH1A1 P00352 5/20 0.43
NPC1 O15118 5/20 0.43
KDM4E B2RXH2 4/20 0.43
RAB9A P51151 4/20 0.43
HPGD P15428 3/20 0.43
ALOX12 P18054 1/20 0.43
NFKB1 P19838 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43
TP53 P04637 3/20 0.42
THRB P10828 1/20 0.42
RECQL P46063 1/20 0.40
GLA P06280 1/20 0.40
GAA P10253 1/20 0.40
MEN1 O00255 2/20 0.39
TUBB1 Q9H4B7 2/20 0.38
MAOB P27338 1/20 0.38
SHMT2 P34897 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30617248 1.00 MAPT (0.47) MAPTSMN1; SMN2ALDH1A1NPC1KDM4E
SCHEMBL25960 0.87 ALDH1A1 (0.47) MAPTSMN1; SMN2ALDH1A1NPC1KDM4E
SCHEMBL29516909 0.87 ALDH1A1 (0.47) MAPTSMN1; SMN2ALDH1A1NPC1KDM4E
SCHEMBL8040923 0.84 S1PR1 (0.43) MAPTSMN1; SMN2ALDH1A1NPC1KDM4E
SCHEMBL387905 0.77 CYP19A1 (0.40) MAPTSMN1; SMN2ALDH1A1NPC1KDM4E
SCHEMBL12196211 0.76 MAOA (0.35) MAPTALDH1A1MAOBTSHRHSD17B10
SCHEMBL8634414 0.76 KDM4E (0.44) MAPTSMN1; SMN2ALDH1A1KDM4EHPGD
SCHEMBL3830957 0.75 CYP19A1 (0.38) MAPTSMN1; SMN2ALDH1A1NPC1KDM4E
SCHEMBL28447729 0.75 KDM4E (0.38) MAPTSMN1; SMN2ALDH1A1NPC1KDM4E
SCHEMBL6140308 0.75 NPC1 (0.35) MAPTSMN1; SMN2ALDH1A1NPC1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 278 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9244354-B2 Method for producing thick film photoresist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2016-01-26 US claimed
US-6010824-A Photosensitive resin composition containing a triazine compound and a pre-sensitized plate using the same, and photosensitive resin composition containing acridine and triazine compounds and a color filter and a pre-sensitized plate using the same TOKYO OHKA KOGYO CO., LTD. (JP) 2000-01-04 US claimed
US-20240239922-A1 PHOTOCURABLE COMPOSITION TOKYO OHKA KOGYO CO., LTD. (JP) 2024-07-18 US disclosed
US-20240192593-A1 PHOTOSENSITIVE COMPOSITION TOKYO OHKA KOGYO CO., LTD. (JP) 2024-06-13 US disclosed
US-20240191003-A1 COMPOSITION AND PHOTOSENSITIVE COMPOSITION TOKYO OHKA KOGYO CO., LTD. (JP) 2024-06-13 US disclosed
US-20240166779-A1 PHOTOCURABLE COMPOSITION AND PATTERN FORMATION METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2024-05-23 US disclosed
US-20240158541-A1 PHOTOCURABLE COMPOSITION AND PATTERN-FORMING METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2024-05-16 US disclosed
US-11981794-B2 Curable composition, cured product, and compound TOKYO OHKA KOGYO CO., LTD. (JP) 2024-05-14 US disclosed
US-20240153687-A1 COMPOSITION HAVING MAGNETOSTRICTIVE PROPERTIES, AND CURED PRODUCT THEREOF TOHOKU UNIVERSITY (JP) 2024-05-09 US disclosed
CN-117999296-A Composition and photosensitive composition 东京应化工业株式会社 2024-05-07 CN disclosed
CN-117980346-A Composition and photosensitive composition 东京应化工业株式会社 2024-05-03 CN disclosed
US-20030039921-A1 Chemically amplified negative photoresist composition for the formation of thick films, photoresist base material and method of forming bumps using the same TOKYO OHKA KOGYO CO., LTD. 2003-02-27 US disclosed
US-6506540-B2 Blend containing photoinitiators TOKYO OHKA KOGYO CO., LTD. (JP) 2003-01-14 US disclosed
US-20020164542-A1 Photosensitive insulating paste composition and photosensitive film made therefrom TOKYO OHKA KOGYO CO., LTD. (JP) 2002-11-07 US disclosed
US-20020031723-A1 Photopolymerizable composition TOKYO OHKA KOGYO CO., LTD. (JP) 2002-03-14 US disclosed
EP-1168080-A2 Photopolymerizable composition TOKYO OHKA KOGYO CO., LTD. (JP) 2002-01-02 EP disclosed
US-6010824-A Photosensitive resin composition containing a triazine compound and a pre-sensitized plate using the same, and photosensitive resin composition containing acridine and triazine compounds and a color filter and a pre-sensitized plate using the same TOKYO OHKA KOGYO CO., LTD. (JP) 2000-01-04 US disclosed
US-5908734-A SELECTIVELY EXPOSING A PHOTOSENSITIVE LAYER WITH A VISIBLE LASER BEAM, HEATING THE EXPOSED PHOTOSENSITIVE LAYER AT A TEMPERATURE OF FROM 36 TO 48.DEGREE. C. FOR 10 SECONDS TO 3 MINUTES, AND DEVELOPING THE PHOTOSENSITIVE LAYER. TOKYO OHKA KOGYO CO., LTD. (JP) 1999-06-01 US disclosed
US-5908720-A CARBON BLACK COATED WITH A RESIN OBTAINED FROM ONE OR MORE POLYMERIZABLE MONOMERS HAVING AT LEAST ONE REACTIVE GROUP SELECTED FROM THE GROUP CONSISTING OF EPOXY, THIOEPOXY, OXAZOLINE, AZILIDINE AND HYDROXYALKYL AMIDE GROUPS TOKYO OHKA KOGYO CO., LTD. (JP) 1999-06-01 US disclosed
US-5714286-A PHOTOPOLYMERIZABLE COMPOUND, PHOTOINITIATOR, LIGHT SHIELDING MATERIAL COMPOSED OF COPPER OXIDE AND IRON, MANGANESE, CHROMIUM, COBALT AND/OR NICKEL OXIDE TOKYO OHKA KOGYO CO., LTD. (JP) 1998-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240192593-A1 PHOTOSENSITIVE COMPOSITION PPOX, ERCC1, ERCC5 MAPT 255/4885SMN1; SMN2 2829/4885ALDH1A1 1414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.