SCHEMBL25960

SCHEMBL25960

COc1ccc(-c2nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n2)cc1OC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
NPC1 O15118 5/20 0.47
SMN1; SMN2 Q16637 5/20 0.47
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
TSHR P16473 3/20 0.47
RAB9A P51151 2/20 0.47
TP53 P04637 1/20 0.47
PDE4A P27815 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
HTT P42858 2/20 0.44
MAPT P10636 3/20 0.44
GAA P10253 2/20 0.44
KDM4E B2RXH2 5/20 0.44
HPGD P15428 2/20 0.44
MAPK1 P28482 2/20 0.44
MPI P34949 1/20 0.44
GFER P55789 1/20 0.44
APOBEC3G Q9HC16 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29516909 1.00 ALDH1A1 (0.47) ALDH1A1NPC1SMN1; SMN2MEN1KMT2A
SCHEMBL499363 0.87 MAPT (0.47) ALDH1A1NPC1SMN1; SMN2MEN1KMT2A
SCHEMBL30617248 0.87 MAPT (0.47) ALDH1A1NPC1SMN1; SMN2MEN1KMT2A
SCHEMBL9368291 0.86 KDM4E (0.60) ALDH1A1NPC1SMN1; SMN2MEN1KMT2A
SCHEMBL8634414 0.84 KDM4E (0.44) ALDH1A1SMN1; SMN2MEN1KMT2AL3MBTL1
SCHEMBL9367306 0.84 NPC1 (0.61) ALDH1A1NPC1SMN1; SMN2MEN1KMT2A
SCHEMBL4415773 0.84 PDGFRB (0.43) ALDH1A1NPC1SMN1; SMN2MEN1KMT2A
SCHEMBL6140308 0.84 NPC1 (0.35) ALDH1A1NPC1SMN1; SMN2MEN1KMT2A
SCHEMBL387905 0.82 CYP19A1 (0.40) ALDH1A1NPC1SMN1; SMN2MEN1KMT2A
SCHEMBL8971568 0.82 ALDH1A1 (0.43) ALDH1A1NPC1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4763204-B2 2011-08-31 JP claimed
US-7332477-B2 Photocleavable DNA transfer agent NITTO DENKO CORPORATION (JP) 2008-02-19 US claimed
WO-2005030253-A9 PHOTOCLEAVABLE DNA TRANSFER AGENT NITTO DENKO CORP (JP) 2005-06-02 WO claimed
US-20050037401-A1 Photocleavable DNA transfer agent NITTO DENKIO CORPORATION (JP) 2005-02-17 US claimed
JP-2003518149-A 2003-06-03 JP claimed
EP-1246882-A2 IMPROVED PAINT REPLACEMENT APPLIQUES 3M Innovative Properties Company (US) 2002-10-09 EP claimed
WO-2001045933-A2 IMPROVED PAINT REPLACEMENT APPLIQUES 3M INNOVATIVE PROPERTIES COMPANY (US) 2001-06-28 WO claimed
EP-0229783-B1 CROSSLINKED PRESSURE-SENSITIVE ADHESIVE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-03-06 EP claimed
US-4731273-A Heat-recoverable closure with crosslinked pressure-sensitive adhesive MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-03-15 US claimed
CN-116615332-B Optically anisotropic laminate and optical element MITSUBISHI CHEMICAL CORP. (JP) 2026-05-26 CN disclosed
EP-4743828-A1 PHOTOCURABLE AS WELL AS THERMALLY CURABLE COMPOSITIONS SUITABLE FOR LOW TEMPERATURE CURING BASF SE (DE) 2026-05-20 EP disclosed
EP-4555025-B1 PHOTOINITIATOR PACKAGE COMPRISING SPECIALISED BISACYLPHOSPHINE OXIDE PHOTOINITIATORS, FURTHER ACYLPHOSPHINE OXIDE PHOTOINITIATORS AND OPTICAL BRIGHTENER SENSITIZERS IGM GROUP B V (NL) 2026-05-13 EP disclosed
US-12624257-B2 Adhesive primer for flexographic plate mounting tape 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-05-12 US disclosed
EP-3902878-B1 PHOTOINITIATORS IGM RESINS ITALIA SRL (IT) 2026-05-06 EP disclosed
US-4751269-A ACRYLIC ACID-ESTER TERPOLYMER WITH AMINO RESIN CROSSLINKER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-06-14 US disclosed
US-4731273-A Heat-recoverable closure with crosslinked pressure-sensitive adhesive MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-03-15 US disclosed
EP-0229783-A1 CROSSLINKED PRESSURE-SENSITIVE ADHESIVE. MINNESOTA MINING & MFG (US) 1987-07-29 EP disclosed
EP-0229111-A1 HEAT-RECOVERABLE CLOSURE WITH CROSSLINKED PRESSURE-SENSITIVE ADHESIVE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-07-22 EP disclosed
WO-1987000189-A1 CROSSLINKED PRESSURE-SENSITIVE ADHESIVE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-01-15 WO disclosed
WO-1987000191-A1 HEAT-RECOVERABLE CLOSURE WITH CROSSLINKED PRESSURE-SENSITIVE ADHESIVE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-01-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624257-B2 Adhesive primer for flexographic plate mounting tape CDH1, PCNA, MYH9 ALDH1A1 1061/4885NPC1 4867/4885SMN1; SMN2 1857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.