Sugi Predict

Sugi Predict / Compounds / SCHEMBL499420

SCHEMBL499420

SCHEMBL499420

O=S(O)c1ccccc1Br

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ G6PD P11413 1/20 0.41
▸ GAA P10253 1/20 0.38
▸ ALDH1A1 P00352 3/20 0.35
▸ CA1 P00915 1/20 0.34
▸ CA2 P00918 1/20 0.34
▸ CA4 P22748 1/20 0.34
▸ CA6 P23280 1/20 0.34
▸ HSD11B1 P28845 1/20 0.34
▸ PLCG1 P19174 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ NPC1 O15118 2/20 0.31
▸ HTT P42858 2/20 0.31
▸ RAB9A P51151 2/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ MGLL Q99685 1/20 0.31
▸ KDM4E B2RXH2 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7520267 0.98 G6PD (0.39) G6PDGAAALDH1A1CA1CA2
SCHEMBL27579679 0.98 G6PD (0.39) G6PDGAAALDH1A1CA1CA2
SCHEMBL27597438 0.98 G6PD (0.39) G6PDGAAALDH1A1CA1CA2
SCHEMBL9153083 0.81 G6PD (0.50) G6PDALDH1A1CA1CA2CA4
SCHEMBL11859134 0.78 G6PD (0.48) G6PDALDH1A1CA2CA4NPC1
SCHEMBL11423411 0.76 PARP1 (0.40) G6PDGAAMEN1KMT2A
SCHEMBL9151925 0.74 G6PD (0.44) G6PDALDH1A1CA1CA2PLCG1
SCHEMBL30018297 0.73 G6PD (0.34) G6PDGAAALDH1A1CA1CA2
SCHEMBL7520260 0.73 G6PD (0.34) G6PDGAAALDH1A1CA1CA2
SCHEMBL9244138 0.72 G6PD (0.68) G6PDALDH1A1CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108191792-A A kind of preparation method of hydrobromic acid Vortioxetine and its intermediate 上海博志研新药物技术有限公司 2018-06-22 — — CN claimed
CN-104628606-A Preparation method of sulfohydrazide compound WANG HUA 2015-05-20 — — CN claimed
CN-103641674-B Method for preparing diaryl sulfone ZHEJIANG ZHONGXIN CHEMICALS CO LTD 2015-04-08 — — CN claimed
CN-103172479-B Preparation method for biaryl through palladium catalysis SHAOXING UNIVERSITY (CN) 2014-10-29 — — CN claimed
CN-104072323-A Symmetric biphenyl preparation method UNIV SHAOXING 2014-10-01 — — CN claimed
CN-103922976-A Asymmetric diaryl sulfone compound and preparation method thereof UNIV SHAOXING 2014-07-16 — — CN claimed
CN-103641674-A Method for preparing diaryl sulfone ZHEJIANG ZHONGXIN CHEMICALS CO LTD 2014-03-19 — — CN claimed
CN-103172479-A Preparation method for biaryl through palladium catalysis UNIV SHAOXING 2013-06-26 — — CN claimed
US-8106110-B2 first portion: bisphenol diglycidylmethacrylate phosphate, 2-hydroxyethylmethacrylate, biphenyl dimethacrylate, dipentaerythritol pentaacrylate, bisphenyl A diglycidylmethacrylate, ethyl-4-dimethyl-aminobenzoate and camphorquinone; second portion: deionized water, aryl sulfinate, thymol blue, and ethanol BISCO, INC. (US) 2012-01-31 — — US claimed
EP-2114357-A1 DUAL APPLICATION MODE SELF-ETCH DENTAL ADHESIVES COMPATIBLE WITH SELF-CURED AND DUAL-CURED COMPOSITES Bisco, Inc. (US) 2009-11-11 — — EP claimed
WO-2008094923-A1 DUAL APPLICATION MODE SELF-ETCH DENTAL ADHESIVES COMPATIBLE WITH SELF-CURED AND DUAL-CURED COMPOSITES BISCO, INC. (US) 2008-08-07 — — WO claimed
US-20080182922-A1 Dual Application Mode Self-Etch Dental Adhesives Compatible with Self-Cured and Dual-Cured Composites BISCO, INC. (US) 2008-07-31 — — US claimed
US-5159082-A Catalytic coupling of an aromatic sulfinic acid with an aromatic halogen compound MITSUBISHI KASEI CORPORATION (JP) 1992-10-27 — — US claimed
EP-0405389-A1 Process for producing an aromatic compound Mitsubishi Chemical Corporation (JP) 1991-01-02 — — EP claimed
CN-112940432-B Polymerizable monomer for dental material, composition, adhesive dental material, and kit 三井化学株式会社 2022-12-30 — — CN disclosed
US-11110038-B2 Dental polymerizable monomers, compositions, adhesive dental materials and kits MITSUI CHEMICALS, INC. (JP) 2021-09-07 — — US disclosed
CN-107427414-B Polymerizable monomer for dental material, composition, adhesive dental material, and kit 三井化学株式会社 2021-07-02 — — CN disclosed
EP-0405389-B1 Process for producing an aromatic compound MITSUBISHI CHEM IND (JP) 1995-01-04 — — EP disclosed
US-5159082-A Catalytic coupling of an aromatic sulfinic acid with an aromatic halogen compound MITSUBISHI KASEI CORPORATION (JP) 1992-10-27 — — US disclosed
EP-0405389-A1 Process for producing an aromatic compound Mitsubishi Chemical Corporation (JP) 1991-01-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11110038-B2 Dental polymerizable monomers, compositions, adhesive dental materials and kits ACTN1, SMCHD1, CAPZA1 G6PD 443/4885GAA 3819/4885ALDH1A1 302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.