Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL499420 | 0.98 | G6PD (0.41) | G6PDGAAALDH1A1CA1CA2 | |
| SCHEMBL27579679 | 0.95 | G6PD (0.39) | G6PDGAAALDH1A1CA1CA2 | |
| SCHEMBL27597438 | 0.95 | G6PD (0.39) | G6PDGAAALDH1A1CA1CA2 | |
| SCHEMBL11859134 | 0.82 | G6PD (0.48) | G6PDALDH1A1CA2CA4TDP1 | |
| SCHEMBL9153083 | 0.79 | G6PD (0.50) | G6PDALDH1A1CA1CA2CA4 | |
| SCHEMBL11423411 | 0.79 | PARP1 (0.40) | G6PDGAAMEN1KMT2A | |
| SCHEMBL10670811 | 0.73 | ALOX15 (0.43) | ALDH1A1CA1CA2CA4MAPK1 | |
| SCHEMBL9151925 | 0.72 | G6PD (0.44) | G6PDALDH1A1CA1CA2PLCG1 | |
| SCHEMBL7515346 | 0.71 | G6PD (0.39) | G6PDALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL7520260 | 0.71 | G6PD (0.34) | G6PDGAAALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106543051-A | A kind of preparation method of Aromatic Sulfide class compound | 南京理工大学 | 2017-03-29 | — | — | CN | claimed |
| CN-103922976-A | Asymmetric diaryl sulfone compound and preparation method thereof | UNIV SHAOXING | 2014-07-16 | — | — | CN | claimed |
| CN-106543051-B | A kind of preparation method of Aromatic Sulfide class compound | 南京理工大学 | 2018-10-02 | — | — | CN | disclosed |
| CN-105906537-B | （Z）The One-step Synthesis method of formula sulfonyl enoic acid ester compounds | 湖南科技学院 | 2017-12-15 | — | — | CN | disclosed |
| CN-106543051-A | A kind of preparation method of Aromatic Sulfide class compound | 南京理工大学 | 2017-03-29 | — | — | CN | disclosed |
| CN-105906537-A | One-pot synthesis method of (Z)-type sulfonyl olefine acid ester compound | 湖南科技学院 | 2016-08-31 | — | — | CN | disclosed |
| CN-103922976-A | Asymmetric diaryl sulfone compound and preparation method thereof | UNIV SHAOXING | 2014-07-16 | — | — | CN | disclosed |
| CN-1464876-A | Novel sulfone derivative and process for producing the same | SUMITOMO CHEMICAL CO (JP) | 2003-12-31 | — | — | CN | disclosed |
| CN-1373112-A | Method for producing allyl halide | SUMITOMO CHEMICAL CO (JP) | 2002-10-09 | — | — | CN | disclosed |
| EP-1231197-A1 | Process for producing allyl halide compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-20020107422-A1 | Process for producing allyl halide compound | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2002-08-08 | — | — | US | disclosed |
| US-5153227-A | Treatment of diabetes and galactosemia complications | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020107422-A1 | Process for producing allyl halide compound | ENY2, ZYX, RPS4Y1 | G6PD 3142/4885GAA 4057/4885ALDH1A1 1133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.