SCHEMBL499783

SCHEMBL499783

CNC(=O)Oc1ccc(C)cc1C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.48
KMT2A Q03164 3/20 0.45
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
PGR P06401 1/20 0.45
GAA P10253 1/20 0.45
PTGS1 P23219 1/20 0.45
MAPK1 P28482 1/20 0.45
HSD17B10 Q99714 1/20 0.45
ACHE P22303 1/20 0.45
HPGD P15428 3/20 0.43
LMNA P02545 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPT P10636 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
MEN1 O00255 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11058046 0.85 SMN1; SMN2 (0.50) ALDH1A1SMN1; SMN2PGRGAAPTGS1
SCHEMBL20660752 0.82 ALDH1A1 (0.47) L3MBTL1KMT2AKDM4EALDH1A1SMN1; SMN2
SCHEMBL22388747 0.82 KMT2A (0.48) L3MBTL1KMT2AKDM4EALDH1A1PGR
SCHEMBL37754 0.80 L3MBTL1 (0.53) L3MBTL1KMT2AKDM4EALDH1A1SMN1; SMN2
SCHEMBL18178840 0.80 MRGPRX4 (0.47) L3MBTL1ALDH1A1SMN1; SMN2PGRGAA
SCHEMBL10930223 0.80 KDM4E (0.67) L3MBTL1KMT2AKDM4EALDH1A1ACHE
SCHEMBL1598721 0.79 L3MBTL1 (0.56) L3MBTL1KMT2AKDM4EALDH1A1SMN1; SMN2
SCHEMBL18178841 0.79 MRGPRX4 (0.49) L3MBTL1KMT2AKDM4EALDH1A1SMN1; SMN2
SCHEMBL13104126 0.79 ALDH1A1 (0.42) L3MBTL1KMT2AKDM4EALDH1A1SMN1; SMN2
SCHEMBL982573 0.79 L3MBTL1 (0.51) L3MBTL1KMT2AKDM4EALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001056358-A2 ENHANCED PROPERTIED PESTICIDES ROHM AND HAAS COMPANY (US) 2001-08-09 WO claimed
US-20260068886-A1 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL OERTH BIO LLC (US) 2026-03-12 US disclosed
US-20260033494-A1 PLANT ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE THEREOF TEXAS A & M UNIV SYS (US) 2026-02-05 US disclosed
US-12458025-B2 Plant antimicrobial compositions and methods of use thereof THE TEXAS A & M UNIVERSITY SYSTEM (US) 2025-11-04 US disclosed
US-12364264-B2 Inhibitors of enzymes that confer pesticide resistance APRESLABS LTD. (GB) 2025-07-22 US disclosed
EP-4580405-A1 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL Oerth Bio LLC (US) 2025-07-09 EP disclosed
CN-115734965-B Aryltetrahydropyridazine derivatives or salts thereof, and insecticides containing the same and methods of use thereof 日本农药株式会社 2025-05-02 CN disclosed
WO-2024050016-A9 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL OERTH BIO LLC (US) 2025-04-03 WO disclosed
CN-119173504-A Piperidone derivative or salt thereof, pest control agent containing the same, and method for using the same 株式会社艾迪科 2024-12-20 CN disclosed
CN-119019293-A Sulfite compounds and their use for disinsection 河南蓝创作物科学有限公司 2024-11-26 CN disclosed
WO-2006053577-A1 NON-AQUEOUS SYSTEM HAVING VISCOELASTIC PROPERTIES DEGUSSA GMBH (DE) 2006-05-26 WO disclosed
WO-2006040113-A2 HETEROCYCLIC DIAMIDE INSECTICIDAL AGENTS SYNGENTA PARTICIPATIONS AG (CH) 2006-04-20 WO disclosed
US-20030118614-A1 Water-in-oil polymer dispersion as additive in active ingredient-comprising compositions GOLDSCHMIDT AG (DE) 2003-06-26 US disclosed
US-6376548-B1 FUNGICIDES; HERBICIDES; INSECTICIDES ROHM AND HAAS COMPANY 2002-04-23 US disclosed
WO-2001056358-A2 ENHANCED PROPERTIED PESTICIDES ROHM AND HAAS COMPANY (US) 2001-08-09 WO disclosed
EP-0135714-B1 SUSTAINED RELEASE COMPOSITIONS FOR BIOLOGICALLY ACTIVE MATERIALS MELAMINE CHEMICALS, INC. (US) 1991-11-06 EP disclosed
EP-0178908-B1 CO-EXTRUSION OF MULTI-COMPONENT ECTOPARASITICIDAL PET COLLARS CONAGRA PET PRODUCTS, INC. (US) 1991-07-31 EP disclosed
US-4433999-A THIOCARBAMATES, CARBAMATE AND AN ANTIDOTE STAUFFER CHEMICAL COMPANY (US) 1984-02-28 US disclosed
US-4299616-A THIOLCARBAMATES IN COMBINATION WITH SUBSTITUTED CARBAMATES STAUFFER CHEMICAL COMPANY (US) 1981-11-10 US disclosed
EP-0038945-A2 Herbicide compositions of extended soil life STAUFFER CHEMICAL COMPANY (US) 1981-11-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12458025-B2 Plant antimicrobial compositions and methods of use thereof DDT, CDA, UROD L3MBTL1 2735/4885KMT2A 2534/4885KDM4E 2654/4885
US-20260033494-A1 PLANT ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE THEREOF MYB, DDT, PDE1C L3MBTL1 1705/4885KMT2A 2836/4885KDM4E 1819/4885
US-20260068886-A1 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL CRBN, STUB1, CUL1 L3MBTL1 191/4885KMT2A 1480/4885KDM4E 928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.