Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.58 |
| ▸ | CTSS | P25774 | 10/20 | 0.58 |
| ▸ | CTSL | P07711 | 4/20 | 0.58 |
| ▸ | CTSB | P07858 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2910891 | 1.00 | CTSK (0.58) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL13263256 | 0.89 | CTSK (0.50) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL3819580 | 0.85 | CTSK (0.52) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL2401238 | 0.85 | CTSK (0.52) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL25360344 | 0.83 | CTSK (0.51) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL25360348 | 0.83 | CTSK (0.51) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL13293164 | 0.83 | CTSS (0.46) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL24981559 | 0.83 | CTSK (0.46) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL5958657 | 0.83 | CTSK (0.56) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL15259348 | 0.83 | CTSK (0.56) | CTSKCTSSCTSLCTSBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080027060-A1 | DIPEPTIDE NITRILES | ALTMANN EVA | 2008-01-31 | — | — | US | disclosed |
| US-20060235220-A1 | Dipeptide nitriles | MISSBACH MARTIN | 2006-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060235220-A1 | Dipeptide nitriles | CTSL, CTSS, CTSB | CTSK 6/4885CTSS 2/4885CTSL 1/4885 |
| US-20080027060-A1 | DIPEPTIDE NITRILES | CTSL, CTSS, CTSB | CTSK 6/4885CTSS 2/4885CTSL 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.