Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | AGXT | P21549 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4998563 | 1.00 | NAAA (0.47) | NAAAESR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4998559 | 0.87 | ESR2 (0.52) | ESR2NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4998557 | 0.87 | ESR2 (0.52) | ESR2NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4994355 | 0.82 | ALDH1A1 (0.46) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL4994349 | 0.82 | ALDH1A1 (0.46) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10011472 | 0.82 | CES2 (0.52) | SMN1; SMN2ALDH1A1MAPTMAPK1KDM4E | |
| SCHEMBL10011469 | 0.82 | CES2 (0.52) | SMN1; SMN2ALDH1A1MAPTMAPK1KDM4E | |
| SCHEMBL12736296 | 0.82 | IDO1 (0.59) | NAAAESR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18437081 | 0.82 | IDO1 (0.59) | NAAAESR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5001639 | 0.81 | ERN1 (0.44) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080119499-A1 | Compositions Havinge Improved 2-Photon Absorbance For Nonlinear Applications | MEMPILE INC. (DE) | 2008-05-22 | — | — | US | claimed |
| US-20080119499-A1 | Compositions Havinge Improved 2-Photon Absorbance For Nonlinear Applications | MEMPILE INC. (DE) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119499-A1 | Compositions Havinge Improved 2-Photon Absorbance For Nonlinear Applications | HTR3D, CRY2, CNDP2 | NAAA 3147/4885ESR2 1252/4885NPC1 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.