SCHEMBL5000668

SCHEMBL5000668

Cn1ncc(C(CCCNC=O)NC(c2ccccc2)(c2ccccc2)c2ccccc2)c1NC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5009203 0.94
SCHEMBL5000661 0.84 DUT (0.34)
SCHEMBL5009200 0.79 KIF11 (0.33)
SCHEMBL5148585 0.78 MEN1 (0.38) MEN1KMT2A
SCHEMBL5148558 0.76 MEN1 (0.33) MEN1KMT2A
SCHEMBL4202432 0.70 CNR1 (0.35) MEN1KMT2A
SCHEMBL4199230 0.69 BRD9 (0.36)
SCHEMBL5007901 0.69 BCDIN3D (0.33)
SCHEMBL4205063 0.69 ALDH1A1 (0.36) KMT2A
SCHEMBL3114368 0.68 GAA (0.34) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1994035-A1 CEPHEM COMPOUNDS AND USE AS ANTIMICROBIAL AGENTS Astellas Pharma Inc. (JP) 2008-11-26 EP disclosed
WO-2007119511-A1 CEPHEM COMPOUNDS AND USE AS ANTIMICROBIAL AGENTS ASTELLAS PHARMA INC. (JP) 2007-10-25 WO disclosed