Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | FNTA | P49354 | 1/20 | 0.30 |
| ▸ | FNTB | P49356 | 1/20 | 0.30 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5000632 | 0.77 | TET2 (0.31) | — | |
| SCHEMBL2119583 | 0.76 | EPHX2 (0.34) | LMNATHRBFNTAFNTBPGGT1B | |
| SCHEMBL3780717 | 0.73 | CA12 (0.33) | THRBFNTAFNTBPGGT1B | |
| SCHEMBL2121048 | 0.72 | TDP1 (0.31) | — | |
| SCHEMBL14120426 | 0.72 | THRB (0.35) | THRBFNTAFNTBPGGT1B | |
| SCHEMBL950316 | 0.72 | ACE2 (0.47) | THRBFNTAFNTBPGGT1B | |
| SCHEMBL828545 | 0.72 | GABRP (0.33) | LMNA | |
| SCHEMBL9501863 | 0.72 | CA1 (0.39) | THRBFNTAFNTBPGGT1B | |
| SCHEMBL11025964 | 0.72 | LMNA (0.42) | LMNATHRBFNTAFNTBPGGT1B | |
| SCHEMBL338900 | 0.71 | TET2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417090-B2 | Water-dispersible polyisocyanate composition, production thereof, and water-based curable composition and application thereof | DAINIPPON INK & CHEMICALS, INC. (JP) | 2008-08-26 | — | — | US | disclosed |
| US-20070049691-A1 | Water-dispersible polyisocyanate composition, production thereof, and water-based curable composition and application thereof | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2007-03-01 | — | — | US | disclosed |